Haglind E, Bengtsson J P, Falk A, Haglund U, Lundgren O, Scherstén T
Res Exp Med (Berl). 1986;186(4):285-94. doi: 10.1007/BF01852305.
Cardiovascular function was studied in a model of intestinal vascular obstruction in cats. To measure right ventricular end diastolic pressure and maximal dP/dt, a tip transducer catheter was placed into the right ventricle. The intestinal vascular obstruction resulted in shock with decreases of blood pressure, cardiac output, and external cardiac work. Small intestinal mucosal lesions were found in all shocked cats. At an increased preload to the heart, right ventricular function was depressed in shocked cats. The model corresponds to one used earlier in the rat, where cardioinhibitory activity in venous blood was found in vitro. In this corresponding model of intestinal shock in the cat a depressed function of the right ventricle of the heart was found in vivo.
在猫的肠血管阻塞模型中研究了心血管功能。为了测量右心室舒张末期压力和最大dP/dt，将尖端换能器导管插入右心室。肠血管阻塞导致休克，血压、心输出量和心脏外部功降低。在所有休克的猫中均发现小肠粘膜损伤。在增加心脏前负荷时，休克猫的右心室功能受到抑制。该模型与早期在大鼠中使用的模型相对应，在该模型中体外发现静脉血中有心脏抑制活性。在猫的这种相应的肠休克模型中，体内发现心脏右心室功能受到抑制。
