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复发性硬脑膜下血肿:一项机构经验。

Recurrent Subdural Hematoma: An Institutional Experience.

作者信息

Swamiyappan Sai Sriram, Krishnaswamy Visvanathan, Visweswaran Vivek, A Sangeetha, Bathala Rav Tej, Karnati Harsh, Gupta Jayesh, K Ganesh

机构信息

Neurosurgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Neurological Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

出版信息

Cureus. 2023 Jul 27;15(7):e42582. doi: 10.7759/cureus.42582. eCollection 2023 Jul.

Abstract

Background Chronic subdural hematoma (CSDH) is a common neurosurgical problem, which offers a good outcome following surgery. In many cases, burr hole irrigation and drainage under local anesthesia can provide satisfactory results. However, recurrence can be a cause for concern for both the surgeon and the patient. While recurrence is not a frequent phenomenon, studies have reported rates of up to 31.6%. Aims and objectives In this study, our objective is to examine a comprehensive range of potential risk factors and provide valuable insights into identifying patients at a higher risk of recurrence to aid in surgical decision-making. Methodology This study employed a prospective and retrospective design, conducted between 2017 and 2021, at Sri Ramachandra Institute of Higher Education and Research. The study received ethical approval from the Institutional Ethics Committee. The research aimed to assess patients who underwent surgery for CSDH, with a particular focus on those who experienced recurrence. Results The average age of patients with recurrence was 71.5 years compared to 65.2 years in the no-recurrence group, but this difference did not show a significant statistical correlation. A significant male predominance was observed, with 27 men and four women affected (out of a total of 147 men and 73 women in the study), resulting in a statistically significant p-value of 0.01. On multivariate analysis, heterogenous subtypes were a significant predictor of recurrence (OR: 8.88, 95% CI: 6.96-16.54, p = 0.01). The mean midline shift in those with recurrence was 11.4 mm compared to 7.09 mm in those without recurrence. This was a statistically significant correlation with a p-value of 0.02. Regarding those with recurrence, 24 patients underwent evacuation using two burr holes, with one placed in the frontal region and another in the parietal region. All of these patients had a subdural drain placed, which was removed on postoperative day 2. The remaining eight patients underwent a mini-craniotomy for evacuation. We had four cases of refractory CSDH, all of whom underwent the second evacuation using burr holes. Three of them underwent evacuation via craniotomy, while the family of the fourth patient did not give consent for the procedure. Conclusion Patient-related factors such as gender, bilateral presentation, and the presence of hypertension and radiological factors such as the presence of heterogenous subtype and a significant midline shift are clues toward a higher chance of recurrence.

摘要

背景 慢性硬膜下血肿(CSDH)是一个常见的神经外科问题,手术治疗效果良好。在许多情况下,局部麻醉下的钻孔冲洗引流可取得满意效果。然而,复发可能是外科医生和患者都担心的问题。虽然复发并不常见,但研究报告的复发率高达31.6%。目的和目标 在本研究中,我们的目标是全面检查一系列潜在风险因素,并为识别复发风险较高的患者提供有价值的见解,以辅助手术决策。方法 本研究采用前瞻性和回顾性设计,于2017年至2021年在斯里兰卡拉马钱德拉高等教育与研究机构进行。该研究获得了机构伦理委员会的伦理批准。该研究旨在评估接受CSDH手术的患者,特别关注那些经历复发的患者。结果 复发患者的平均年龄为71.5岁,无复发组为65.2岁,但这种差异没有显示出显著的统计学相关性。观察到男性明显占主导,有27名男性和4名女性受影响(研究中共有147名男性和73名女性),p值为0.01,具有统计学意义。多因素分析显示,异质性亚型是复发的显著预测因素(OR:8.88,95%CI:6.96 - 16.54,p = 0.01)。复发患者的平均中线移位为11.4 mm,无复发患者为7.09 mm。这具有统计学显著相关性,p值为0.02。关于复发患者,24例患者通过两个钻孔进行血肿清除,一个位于额部区域,另一个位于顶叶区域。所有这些患者均放置了硬膜下引流管,并在术后第2天拔除。其余8例患者接受了小骨窗开颅血肿清除术。我们有4例难治性CSDH患者,所有患者均通过钻孔进行了第二次血肿清除。其中3例通过开颅手术进行血肿清除,第四例患者的家属未同意进行该手术。结论 与患者相关的因素,如性别、双侧表现、高血压的存在,以及放射学因素,如异质性亚型的存在和明显的中线移位,提示复发几率较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d315/10460295/e8b38d8cdd8c/cureus-0015-00000042582-i01.jpg

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