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慢性硬膜下血肿

Chronic subdural hematoma.

作者信息

Yadav Yad R, Parihar Vijay, Namdev Hemant, Bajaj Jitin

机构信息

Department of Neurosurgery, NSCB Medical College, Jabalpur, Madhya Pradesh, India.

出版信息

Asian J Neurosurg. 2016 Oct-Dec;11(4):330-342. doi: 10.4103/1793-5482.145102.

DOI:10.4103/1793-5482.145102
PMID:27695533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4974954/
Abstract

Chronic subdural hematoma (CSDH) is one of the most common neurosurgical conditions. There is lack of uniformity in the treatment of CSDH amongst surgeons in terms of various treatment strategies. Clinical presentation may vary from no symptoms to unconsciousness. CSDH is usually diagnosed by contrast-enhanced computed tomography scan. Magnetic resonance imaging (MRI) scan is more sensitive in the diagnosis of bilateral isodense CSDH, multiple loculations, intrahematoma membranes, fresh bleeding, hemolysis, and the size of capsule. Contrast-enhanced CT or MRI could detect associated primary or metastatic dural diseases. Although definite history of trauma could be obtained in a majority of cases, some cases may be secondary to coagulation defect, intracranial hypotension, use of anticoagulants and antiplatelet drugs, etc., Recurrent bleeding, increased exudates from outer membrane, and cerebrospinal fluid entrapment have been implicated in the enlargement of CSDH. Burr-hole evacuation is the treatment of choice for an uncomplicated CSDH. Most of the recent trials favor the use of drain to reduce recurrence rate. Craniotomy and twist drill craniostomy also play a role in the management. Dural biopsy should be taken, especially in recurrence and thick outer membrane. Nonsurgical management is reserved for asymptomatic or high operative risk patients. The steroids and angiotensin converting enzyme inhibitors may also play a role in the management. Single management strategy is not appropriate for all the cases of CSDH. Better understanding of the nature of the pathology, rational selection of an ideal treatment strategy for an individual patient, and identification of the merits and limitations of different surgical techniques could help in improving the prognosis.

摘要

慢性硬膜下血肿(CSDH)是最常见的神经外科疾病之一。在外科医生中,对于CSDH的治疗,各种治疗策略缺乏一致性。临床表现可能从无症状到昏迷不等。CSDH通常通过增强计算机断层扫描来诊断。磁共振成像(MRI)扫描在诊断双侧等密度CSDH、多个分隔、血肿内包膜、新鲜出血、溶血以及包膜大小方面更敏感。增强CT或MRI可以检测相关的原发性或转移性硬脑膜疾病。虽然大多数病例可以获得明确的外伤史,但有些病例可能继发于凝血缺陷、颅内低压、使用抗凝剂和抗血小板药物等。复发性出血、外膜渗出物增加和脑脊液潴留与CSDH的扩大有关。钻孔引流是单纯性CSDH的首选治疗方法。最近的大多数试验支持使用引流管以降低复发率。开颅手术和锥颅术在治疗中也发挥作用。应进行硬脑膜活检,尤其是在复发和外膜增厚的情况下。非手术治疗适用于无症状或手术风险高的患者。类固醇和血管紧张素转换酶抑制剂在治疗中也可能发挥作用。单一的治疗策略并不适用于所有CSDH病例。更好地了解病理性质、为个体患者合理选择理想的治疗策略以及识别不同手术技术的优缺点有助于改善预后。

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The role of corticosteroids in the management of chronic subdural hematoma: a systematic review.皮质类固醇在慢性硬脑膜下血肿治疗中的作用:系统评价。
Eur J Neurol. 2012 Nov;19(11):1397-403. doi: 10.1111/j.1468-1331.2012.03768.x. Epub 2012 May 29.
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[Incidence and clinical impact of seizures after surgery for chronic subdural haematoma].
美国的硬膜下血肿与医疗事故:314例患者的分析
Trauma Surg Acute Care Open. 2025 May 30;10(2):e001462. doi: 10.1136/tsaco-2024-001462. eCollection 2025.
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The safety and feasibility of anticoagulant resumption following middle meningeal artery embolization in patients with subacute subdural hematomas.亚急性硬膜下血肿患者脑膜中动脉栓塞后抗凝恢复的安全性和可行性。
Interv Neuroradiol. 2025 Jun 2:15910199251339553. doi: 10.1177/15910199251339553.
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Embolization of Middle Meningeal Artery in Patients with Chronic Subdural Hematoma: A Systematic Review and Meta-Analysis of Randomized-Controlled Clinical Trials.慢性硬膜下血肿患者脑膜中动脉栓塞治疗:随机对照临床试验的系统评价和Meta分析
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Letter to Editor for "Subgaleal drainage with one burr-hole for chronic subdural hematomas: Our Two-Years' Experience".致《单钻孔硬脑膜下引流治疗慢性硬膜下血肿:我们的两年经验》编辑的信
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Factors predicting recurrence of chronic subdural haematoma: the influence of intraoperative irrigation and low-molecular-weight heparin thromboprophylaxis.预测慢性硬脑膜下血肿复发的因素:术中灌洗和低分子肝素预防血栓的影响。
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