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硅油轻填充治疗持续性全层黄斑裂孔的封闭率及模式。

Closure rates and patterns after light silicone oil tamponade for persistent full-thickness macular holes.

机构信息

Department of Ophthalmology, Medical University of Graz, Auenbruggerplatz 4, 8036, Graz, Austria.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2023 Dec;261(12):3481-3488. doi: 10.1007/s00417-023-06215-w. Epub 2023 Aug 29.

Abstract

PURPOSE

To report outcomes of re-vitrectomy using light silicone oil (SO) tamponade for persistent macular holes (MHs).

METHODS

We reviewed cases of patients with full-thickness MHs that underwent pars plana vitrectomy (PPV) with air/gas and were re-vitrectomized using light SO tamponade after primary non-closure (persistent MHs). Outcome measures included anatomic closure rates and patterns confirmed by optical coherence tomography (OCT) and changes in best-corrected visual acuity (BCVA).

RESULTS

A total of 42 eyes of 41 patients with unsuccessful primary PPV with air/gas were included. After re-vitrectomy with light SO (1000-centistoke), 29 (69%) eyes demonstrated type 1 closure without neurosensory defects in OCT scans, whereas 9 eyes (21%) showed type 2 closure with persisting neurosensory defects. Available data (n = 21) showed a significant mean improvement of BCVA from 0.99 logMAR (SD 0.25, range 0.7-1.3) preoperatively to 0.74 logMAR (SD 0.42, range 0.2-1.5) postoperatively (p = 0.035).

CONCLUSION

The treatment of persistent MHs with PPV and light SO tamponade resulted in high closure rates.

摘要

目的

报告使用轻硅油(SO)进行再玻璃体切割术治疗持续性黄斑裂孔(MH)的结果。

方法

我们回顾了经巩膜平坦部玻璃体切除术(PPV)联合空气/气体治疗且初次未闭合(持续性 MH)后使用轻 SO 进行再玻璃体切割术的全层 MH 患者的病例。观察指标包括光学相干断层扫描(OCT)证实的解剖闭合率和模式,以及最佳矫正视力(BCVA)的变化。

结果

共纳入 41 例 42 只眼,这些眼均为初次 PPV 联合空气/气体治疗失败。经轻 SO(1000 厘沲)再玻璃体切割术后,29 只眼(69%)在 OCT 扫描中表现为 1 型闭合且无神经感觉缺陷,9 只眼(21%)表现为 2 型闭合伴持续神经感觉缺陷。现有数据(n=21)显示,BCVA 从术前的 0.99 logMAR(SD 0.25,范围 0.7-1.3)显著提高至术后的 0.74 logMAR(SD 0.42,范围 0.2-1.5)(p=0.035)。

结论

PPV 联合轻 SO 治疗持续性 MH 可获得较高的闭合率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df18/10667392/d5afe0d5b729/417_2023_6215_Fig1_HTML.jpg

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