Björkholm B, Elgefors B
Scand J Infect Dis. 1986;18(4):375-8. doi: 10.3109/00365548609032350.
A cerebellar aspergilloma simulating brain tumour in a 48-year-old woman with alveolar proteinosis is described. The course of the disease was recurrent. Despite neurosurgery, ventricular drainage, amphotericin B, flucytosine and other antifungal agents, the disease was ultimately fatal. The diagnostic and therapeutic problems of aspergillosis in the central nervous system are discussed. Suspicion and serology might lead to early diagnosis and a better prognosis.
本文描述了一名患有肺泡蛋白沉积症的48岁女性，其小脑曲霉菌瘤酷似脑肿瘤。病程呈复发性。尽管进行了神经外科手术、脑室引流、使用两性霉素B、氟胞嘧啶及其他抗真菌药物治疗，该疾病最终仍导致死亡。文中讨论了中枢神经系统曲霉菌病的诊断和治疗问题。提高警惕并进行血清学检查可能有助于早期诊断并改善预后。
