Department of Cardiology, Yongkang People's Hospital, Yongkang, Zhejiang, 321300, China.
Department of Cardiology, Yongkang Hospital, Yongkang, Zhejiang, 321300, China.
BMC Cardiovasc Disord. 2023 Aug 29;23(1):427. doi: 10.1186/s12872-023-03468-5.
In recent years, there has been growing interest in exploring the relationship between activities of daily living (ADL) and cardiovascular diseases. This retrospective cross-sectional study aimed to investigate the association of ADL measured by Barthel index (BI) with periprocedural myocardial infarction (PMI) and injury following percutaneous coronary intervention (PCI).
Enrolled patients were stratified into impaired and unimpaired ADL groups according to their BI scores. Logistic regressions were conducted to explore the association of ADL on admission with periprocedural myocardial injury and infarction. Restricted cubic spline (RCS) curve and subgroup analysis were also performed.
Totally, 16.4% of patients suffered from PMI; the mean age was 65.8 ± 10.4 years old. RCS analysis showed that the morbidity of periprocedural myocardial infarction and injury showed a downward tendency with increasing BI scores. Multivariable logistic regression analysis demonstrated that impaired ADL was an independent risk factor for periprocedural myocardial infarction (OR = 1.190, 95% CI [1.041, 1.360], P = 0.011) and injury (OR = 1.131, 95% CI [1.017, 1.257], P = 0.023). Subgroup analysis showed that the association between ADL and PMI was founded in several subgroups, while the association between ADL and periprocedural myocardial injury was founded only in BMI ≥ 24 kg/m subgroup.
Impaired ADL at hospital admission was an independent risk factor for periprocedural myocardial infarction and injury among patients following PCI.
近年来,人们越来越关注日常生活活动(ADL)与心血管疾病之间的关系。这项回顾性的横断面研究旨在探讨 Barthel 指数(BI)评估的 ADL 与经皮冠状动脉介入治疗(PCI)围术期心肌梗死(PMI)和损伤之间的关系。
根据 BI 评分,将纳入的患者分为 ADL 受损和未受损组。采用 logistic 回归分析 ADL 与围术期心肌损伤和梗死的关系。还进行了限制性三次样条(RCS)曲线和亚组分析。
共有 16.4%的患者发生 PMI;平均年龄为 65.8±10.4 岁。RCS 分析表明,随着 BI 评分的增加,围术期心肌梗死和损伤的发病率呈下降趋势。多变量 logistic 回归分析表明,ADL 受损是围术期心肌梗死(OR=1.190,95%CI[1.041,1.360],P=0.011)和损伤(OR=1.131,95%CI[1.017,1.257],P=0.023)的独立危险因素。亚组分析表明,ADL 与 PMI 之间的关系在多个亚组中存在,而 ADL 与围术期心肌损伤之间的关系仅在 BMI≥24kg/m 亚组中存在。
入院时 ADL 受损是 PCI 后患者围术期心肌梗死和损伤的独立危险因素。