认知功能障碍与急性心肌梗死后虚弱患者的身体功能障碍相关。
Cognitive dysfunction correlates with physical impairment in frail patients with acute myocardial infarction.
机构信息
University of Campania "Luigi Vanvitelli", Naples, Italy.
ASL Avellino, Avellino, Italy.
出版信息
Aging Clin Exp Res. 2022 Jan;34(1):49-53. doi: 10.1007/s40520-021-01897-w. Epub 2021 Jun 8.
Abstract
BACKGROUND
To the best of our knowledge, the association of physical impairment and cognitive decline has never been investigated in frail patients with acute myocardial infarction.
AIM
The aim of our study is to assess the correlation between physical and cognitive dysfunction in frail patients with ST-elevation myocardial infarction (STEMI).
METHODS
We examined consecutive frail patients with first STEMI treated with primary percutaneous coronary intervention (PPCI). All patients were evaluated via Mini Mental State Examination (MMSE) and 5-m gait speed test after PPCI.
RESULTS
A total of 871 frail patients with suspected STEMI were admitted and 301 patients successfully completed the study. We found that the gait speed significantly correlated with the MMSE score (r: 0.771; p: < 0.001). The independent effects on MMSE score were confirmed in a linear multivariate analysis.
CONCLUSIONS
Taken together, our findings indicate that an assessment of both cognitive and physical conditions should be included in the comprehensive geriatric evaluation of hospitalized older STEMI patients.
摘要
背景
据我们所知，身体功能障碍与认知能力下降之间的关联在患有急性心肌梗死的虚弱患者中从未被研究过。
目的
我们的研究旨在评估 ST 段抬高型心肌梗死（STEMI）虚弱患者的身体和认知功能障碍之间的相关性。
方法
我们检查了接受直接经皮冠状动脉介入治疗（PPCI）的首诊 STEMI 合并衰弱的连续患者。所有患者均在 PPCI 后接受 Mini 精神状态检查（MMSE）和 5 米步行速度测试。
结果
共有 871 名疑似 STEMI 的虚弱患者入院，其中 301 名患者成功完成了研究。我们发现，步态速度与 MMSE 评分显著相关（r：0.771；p：<0.001）。在多元线性分析中，确认了对 MMSE 评分的独立影响。
结论
总之，我们的研究结果表明，在对住院老年 STEMI 患者进行全面老年评估时，应同时评估认知和身体状况。
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