Nooreen Zulfa, Rai Awani Kumar, Summayya Fariha, Tandon Sudeep
PSIT - Pranveer Singh Institute of Technology (Pharmacy) Bhauti, Kanpur Uttar Pradesh 209305, India.
Integral Informatic and Research Center-1 (IIRC-1) Intergral University Lucknow Uttar Pradesh 226026, India.
Curr Diabetes Rev. 2024;20(3):e290823220456. doi: 10.2174/1573399820666230829094724.
The rising in diabetes incidents has clearly become one main worldwide health problem. Individuals suffering from diabetes are still more susceptible to many long-term and short-term side effects, which most often cause fatalities. Even though chemically synthesized anti-diabetic entities are capable of helping manage and treat, there has been significant risks related with their prolong and repetitive use. Hence, there is a requirement for safer and novel approaches that might be formed and utilized.
Aim of the present review is to explain the naturally occurring phytochemicals and novel approach as anti-diabetic agents in the treatment of diabetes and its related issues.
A survey of Google scholar, Research Gate, Pubmed, Science Direct, NCBI database was carried out conducted to determine a most hopeful phytochemicals and novel drug delivery systems in the management of diabetes.
The study stressed the significance of phytomolecules and some novel approaches researched or reported in the literature for the management and cure of diabetes. It is suggested that changes in lifestyle can help patients and like nutritional support, assessment and lifestyle guidance must be individualized based on physical and functional capacity. Further evaluations and improved preventative medicine were the result of improving patient outcomes.
Conventional or synthetic drugs provide relief for short time but nanoformulations of phytomolecules offer an improved therapeutic with fewer negative side effects. Herbal medicines are rich in phytoconstituents and possess variety of health benefits. This review is compilation of phytoconstituents and novel drug delivery system of phytomolecules i.e. nanoparticles, niosomes, microsphere, microparticle and others.
糖尿病发病率的上升显然已成为一个主要的全球健康问题。糖尿病患者仍然更容易受到许多长期和短期副作用的影响，这些副作用常常导致死亡。尽管化学合成的抗糖尿病药物能够帮助控制和治疗，但长期和重复使用它们存在重大风险。因此，需要开发和利用更安全、新颖的方法。
本综述的目的是解释天然存在的植物化学物质以及作为抗糖尿病药物治疗糖尿病及其相关问题的新方法。
对谷歌学术、Research Gate、PubMed、ScienceDirect、NCBI数据库进行了调查，以确定在糖尿病管理中最有前景的植物化学物质和新型药物递送系统。
该研究强调了植物分子以及文献中研究或报道的一些新方法在糖尿病管理和治疗中的重要性。建议生活方式的改变可以帮助患者，比如营养支持，评估和生活方式指导必须根据身体和功能能力进行个体化。进一步的评估和改进的预防医学是改善患者预后的结果。
传统或合成药物只能提供短期缓解，而植物分子的纳米制剂提供了更好的治疗效果，副作用更少。草药富含植物成分，具有多种健康益处。本综述汇编了植物成分以及植物分子的新型药物递送系统，即纳米颗粒、脂质体、微球、微粒等。
