Day Surgery Center, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, China.
Department of Infection Management, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, China.
Epidemiol Infect. 2023 Aug 30;151:e149. doi: 10.1017/S0950268823001371.
This study aimed to summarise the findings of the studies assessing the effectiveness of ultraviolet C (UV-C) room disinfection in reducing the incidence rate of healthcare-associated multi-drug-resistant organism (MDRO) infections. A systematic screening was conducted using PubMed, EMBASE, and Scopus for randomised controlled trials (RCTs), quasi-experimental studies, and before-after studies, which assessed the efficacy of the UV-C disinfectant system in reducing the incidence of MDRO infections. A random-effects model was used for the analysis. Effect sizes were described as incidence rate ratio (IRR) with 95% confidence intervals (CI). Nine studies were included, all of which were conducted in the USA. No statistically significant reduction in (CD) (IRR: 0.90, 95% CI; 0.62-1.32) and vancomycin-resistant enterococcal (VRE) infection rates (IRR 0.72, 95% CI; 0.38-1.37) was observed with the use of UV-C, but the risk of Gram-negative rod infection was reduced (IRR 0.82, 95% CI; 0.68-0.99).
本研究旨在总结评估紫外线 C（UV-C）房间消毒在降低医疗机构相关多重耐药菌（MDRO）感染发生率方面有效性的研究结果。使用 PubMed、EMBASE 和 Scopus 对随机对照试验（RCT）、准实验研究和前后对照研究进行了系统筛选，这些研究评估了 UV-C 消毒剂系统在降低 MDRO 感染发生率方面的功效。采用随机效应模型进行分析。效应大小用发病率比（IRR）和 95%置信区间（CI）表示。纳入了 9 项研究，均在美国进行。使用 UV-C 并未显著降低耐碳青霉烯类肺炎克雷伯菌（CR-KP）[CD]（IRR：0.90，95%CI；0.62-1.32）和万古霉素耐药肠球菌（VRE）感染率（IRR 0.72，95%CI；0.38-1.37），但革兰氏阴性杆菌感染的风险降低（IRR 0.82，95%CI；0.68-0.99）。
