Okar Lina, Mesraoua Boulenouar, Deleu Dirk
Department of Medical Education, Hamad Medical Corporation, Doha, Qatar.
Department of Neurology, Hamad Medical Corporation, Doha, Qatar.
Int Med Case Rep J. 2023 Aug 23;16:473-479. doi: 10.2147/IMCRJ.S419609. eCollection 2023.
Mucormycosis is an opportunistic infection that affects immunocompromised patients, especially those with uncontrolled diabetes. Clinical presentation depends on the site of infection. Complications arise when the pathogen invades the host tissue causing vascular necrosisand distortion. Disease course is fast, and most of the time it has a poor or fatal outcome. Rhino-orbito-cerebral mucormycosis is the most common presenting form. Although initial complaints include fever, sinusitis, nasal discharge, headache, facial pain, and swelling, it should be kept in mind that patients might present during the complication period with a hemiparesis or altered mental status. Here, we present a case of patient who presented with a stroke and further workup revealed the presence of mucormycosis. According to our knowledge, this is the first case of mucormycosis complicated with stroke that was managed with thrombolysis.
毛霉病是一种侵袭免疫功能低下患者的机会性感染，尤其是那些患有未控制的糖尿病患者。临床表现取决于感染部位。当病原体侵入宿主组织导致血管坏死和变形时，就会出现并发症。病程进展迅速，大多数情况下预后不良或致命。鼻眶脑毛霉病是最常见的表现形式。虽然最初的症状包括发热、鼻窦炎、流涕、头痛、面部疼痛和肿胀，但应记住，患者在并发症期可能会出现偏瘫或精神状态改变。在此，我们报告一例以中风就诊的患者，进一步检查发现患有毛霉病。据我们所知，这是首例通过溶栓治疗的并发中风的毛霉病病例。
