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躁狂:一种可能的脑膜脑炎的非典型表现。

Mania: An atypical presentation of probable meningoencephalitis.

作者信息

Hudson Ann, Bobo Daniel, Rueda Prada Libardo, Dumic Igor, Petcu Emilia, Cardozo Milena, Shweta Fnu

机构信息

Mayo Clinic Alix School of Medicine, Rochester, MN, USA.

Hospital Medicine, Mayo Clinic Health System, Eau Claire, WI, USA.

出版信息

IDCases. 2023 Jun 9;33:e01817. doi: 10.1016/j.idcr.2023.e01817. eCollection 2023.

Abstract

, also known as Group B Streptococcus (GBS), is a common pathogen in the neonatal period, causing meningitis and sepsis. In non-pregnant adults it is an unusual cause of meningitis. We report about an elderly female with several risk factors for invasive GBS infection who developed GBS meningoencephalitis one month after treatment for COVID-19 upper respiratory tract infection. The patient presented with mania, and the classic triad of headache, neck stiffness, and fever was absent which contributed to the delay in diagnosis. Following initiation of treatment with intravenous ceftriaxone she attained full recovery, and her behavior returned to baseline. This case illustrates an unusual presentation of an emerging infection and should alert clinicians about this presentation. By reporting this case we want to raise awareness about mania as a presenting feature of meningoencephalitis. This should lead to more timely diagnosis and better outcomes for future patients.

摘要

[病原体名称],也称为B组链球菌(GBS),是新生儿期常见的病原体,可引起脑膜炎和败血症。在非妊娠成人中,它是脑膜炎的罕见病因。我们报告了一名老年女性,她有几个侵袭性GBS感染的危险因素,在治疗COVID-19上呼吸道感染一个月后发生了GBS脑膜脑炎。患者表现为躁狂,缺乏头痛、颈部僵硬和发热的典型三联征,这导致了诊断延迟。在开始静脉注射头孢曲松治疗后,她完全康复,行为恢复到基线水平。该病例说明了一种新发感染的不寻常表现,应提醒临床医生注意这种表现。通过报告这个病例,我们希望提高对躁狂作为脑膜脑炎表现特征的认识。这应该会为未来的患者带来更及时的诊断和更好的治疗结果。

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