Iwai-Kumashiro Naoko, Kono Masamitsu, Morita Yohei, Tamagawa Shunji, Hotomi Muneki
Department of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama, Japan.
IDCases. 2025 Jun 3;41:e02276. doi: 10.1016/j.idcr.2025.e02276. eCollection 2025.
A previously healthy 79-year-old man who developed a retropharyngeal abscess secondary to Group B (GBS) infections is reported. Comprehensive imaging evaluation revealed a retropharyngeal abscess due to pyogenic spondylitis was made, which progressed to an epidural abscess and descending necrotizing mediastinitis. Successful treatment with surgical drainage and antimicrobial chemotherapy suggests that with prompt diagnosis and appropriate management, outcomes can be favorable even in severe presentations. The pathogenesis of invasive GBS infection in the elderly is multifactorial. Immune senescence and bacterial translocation may play an important role. This case report highlights an important shift in the microbiological landscape of invasive GBS infections, particularly in adults.
据报道，一名既往健康的79岁男性因B组链球菌（GBS）感染继发咽后脓肿。综合影像学评估显示为化脓性脊柱炎所致的咽后脓肿，该脓肿进展为硬膜外脓肿和下行性坏死性纵隔炎。手术引流和抗菌化疗的成功治疗表明，即使在病情严重的情况下，及时诊断和适当处理也可取得良好预后。老年人侵袭性GBS感染的发病机制是多因素的。免疫衰老和细菌易位可能起重要作用。本病例报告突出了侵袭性GBS感染微生物格局的重要转变，尤其是在成年人中。
