Department of Physical Therapy, University of Delaware, Newark, DE, USA.
Biomechanics and Movement Science (BIOMS) Program, University of Delaware, Newark, DE, USA.
Neurorehabil Neural Repair. 2023 Sep;37(9):628-639. doi: 10.1177/15459683231195039. Epub 2023 Aug 30.
Exercise priming, pairing high intensity exercise with a motor learning task, improves retention of upper extremity tasks in individuals after stroke, but has shown no benefit to locomotor learning. This difference may relate to the type of learning studied. Upper extremity studies used explicit, strategic tasks; locomotor studies used implicit sensorimotor adaptation (split-belt treadmill). Since walking is an important rehabilitation goal, it is crucial to understand under which circumstances exercise priming may improve retention of a newly learned walking pattern.
Determine the impact of exercise priming on explicit, strategic locomotor learning task retention in chronic stroke survivors.
Chronic stroke survivors (>6 months) performed 2 treadmill walking sessions. Visual feedback was used to train increased step length. Participants were assigned to control group (no exercise), continuous exercise (5 minutes high intensity), or long-interval exercise (15 minutes high/moderate intervals). After day 1 learning, participants either rested or performed exercise. On day 2, retention of the learned walking pattern was tested.
All groups learned on day 1 ( < .001). The 2 priming groups showed significant changes in blood lactate and heart rate after exercise priming, the resting control group did not ( < .001). On day 2, there was no significant between-group difference in cued or un-cued task retention ( = .963 and .287, respectively).
Exercise priming did not affect retention of an explicit locomotor task in chronic stroke survivors. Further work should explore subgroups of individuals for whom priming may have selective clinical benefit to locomotor learning.ClinicalTrials.gov Identifier: NCT03726047.
运动启动，即将高强度运动与运动学习任务相结合，可提高中风后个体上肢任务的保持能力，但对运动学习没有益处。这种差异可能与所研究的学习类型有关。上肢研究使用明确的、策略性的任务；运动研究使用内隐的感觉运动适应（分带跑步机）。由于行走是重要的康复目标，因此了解在何种情况下运动启动可以改善新习得的行走模式的保持能力至关重要。
确定运动启动对慢性中风幸存者明确的、策略性的运动学习任务保持的影响。
慢性中风幸存者（>6 个月）进行了 2 次跑步机行走训练。使用视觉反馈来训练增加步长。参与者被分配到对照组（无运动）、连续运动组（5 分钟高强度运动）或长间隔运动组（15 分钟高强度/中强度间隔运动）。在第 1 天学习后，参与者要么休息，要么进行运动。在第 2 天，测试习得行走模式的保持情况。
所有组在第 1 天均有学习（ < .001）。在运动启动后，2 个启动组的血乳酸和心率均有显著变化，而休息对照组则没有（ < .001）。在第 2 天，提示或非提示任务的保留没有显著的组间差异（分别为 = .963 和.287）。
运动启动并未影响慢性中风幸存者显性运动任务的保持。进一步的研究应该探索对运动学习具有选择性临床益处的个体亚组。临床试验注册号：NCT03726047。
