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[银屑病和血清阴性类风湿关节炎中的组织相容性抗原]

[Histocompatibility antigens in psoriatic and seronegative rheumatoid arthritis].

作者信息

Benevolenskaia L I, Erdes Sh, Iakovleva D B, Groppa L P

出版信息

Ter Arkh. 1986;58(7):17-9.

PMID:3764734
Abstract

Antigens of A and B loci of the histocompatibility system were investigated in 173 patients: 35 with psoriatic arthritis, 38 with seronegative rheumatoid arthritis, 80 with seropositive rheumatoid arthritis and 20 with uncomplicated psoriasis. The results of typification showed that B13 antigen was common in every other patient with uncomplicated psoriasis or psoriatic arthritis, and in the patients with seronegative rheumatoid arthritis it was much more common than in the patients with seropositive rheumatoid arthritis or in the population. Proceeding from the authors' and literature data it was assumed that as a matter of fact, part of the patients (about 15%) with seronegative rheumatoid arthritis had rheumatoid-like psoriatic arthritis without skin manifestations.

摘要

对173例患者的组织相容性系统A和B位点抗原进行了研究:35例银屑病关节炎患者、38例血清阴性类风湿关节炎患者、80例血清阳性类风湿关节炎患者和20例单纯性银屑病患者。分型结果显示,B13抗原在每例单纯性银屑病或银屑病关节炎患者中都很常见,在血清阴性类风湿关节炎患者中比血清阳性类风湿关节炎患者或人群中更为常见。根据作者和文献数据推测,事实上,部分血清阴性类风湿关节炎患者(约15%)患有类风湿样银屑病关节炎但无皮肤表现。

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