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原发性慢性肾盂肾炎还是弥漫性肾脏病变?(对泌尿外科X线检查数据解读的批判性评论)

[Primary chronic pyelonephritis or diffuse kidney lesions? (critical comments on interpreting the data from a urologic x-ray examination)].

作者信息

Shpigel' A N

出版信息

Ter Arkh. 1986;58(8):120-7.

PMID:3764754
Abstract

Analyzing correlation of the results of excretory urography and histological findings (kidney biopsy) in 2852 nephrological patients the author has come to a conclusion that changes in the structure of the pelvicaliceal system (PCS) which are usually regarded as x-ray signs of primary chronic pyelonephritis (PCPN), are not typical of this disease and can be also observed in patients with diffuse renal lesions. PCS changes of "pyelonephritic" type were detected in 2470 patients, histologically in 698 (28.1%), in them PCPN morphological signs were detected, and 1772 patients (71.9%) had different diffuse renal lesions. In the author's opinion, PCS changes in such patients could result from an increase in the kidney mass caused by edema or sclerosis of morphological elements of the renal tissue. The absence of both in 382 patients with diffuse renal lesions was not accompanied by PCS changes. The author has been of opinion that identity of the pictures of PCS changes is in the unity of the existing process: compression of the PCS fragments as a result of edema or sclerosis. Therefore PCPN absolute x-ray criteria could be based on the histological confirmation of this disease and what is most important on the absence of morphological data in favor of any diffuse renal lesion or on the detection of the normal renal tissue. In the interpretation of changes in the PCS structure to avoid diagnostic errors the author insists upon the necessity of regarding these changes, first of all, as a result of renal lesion only with subsequent patient's examination to determine the true nature of renal lesion. A decisive point in this respect is a histological study.

摘要

通过分析2852例肾病患者排泄性尿路造影结果与组织学检查结果(肾活检)的相关性,作者得出结论:肾盂肾盏系统(PCS)结构的改变通常被视为原发性慢性肾盂肾炎(PCPN)的X线征象,但并非该疾病所特有,在弥漫性肾病变患者中也可观察到。2470例患者检测到“肾盂肾炎型”PCS改变,其中698例(28.1%)经组织学检查发现有PCPN形态学征象,1772例(71.9%)有不同的弥漫性肾病变。作者认为,此类患者的PCS改变可能是由于肾组织形态学成分水肿或硬化导致肾脏体积增大所致。382例弥漫性肾病变患者中两者均无的情况未伴有PCS改变。作者认为,PCS改变图像的一致性在于现有过程的统一性:由于水肿或硬化导致PCS片段受压。因此,PCPN的绝对X线标准可基于该疾病的组织学证实,最重要的是不存在支持任何弥漫性肾病变的形态学数据或检测到正常肾组织。在解释PCS结构改变以避免诊断错误时,作者坚持首先必须将这些改变视为仅由肾脏病变引起,随后对患者进行检查以确定肾脏病变的真正性质。在这方面,一个决定性的要点是组织学研究。

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