Neĭmark A I, Mazyrko A V
Ter Arkh. 1986;58(8):23-7.
The state of microcirculation and the system of hemostasis were studied over time in 52 patients with chronic calculous pyelonephritis. Investigations were performed before operation, after 2-4 days, 5-7 days and on discharge. The patients were divided into 2 groups: with chronic pyelonephritis in the phase of active inflammation and with chronic pyelonephritis in the phase of remission. Marked disorders in the system of hemostasis characterized by hyperfibrinogenemia, thrombinemia, a decrease in the heparincofactor plasma activity, activation of platelet hemostasis, a decrease in CPa-dependent fibrinolysis were noted in the patients with calculous pyelonephritis in the phase of active inflammation. These shifts were combined with disorders in the microcirculatory system: intermittent blood flow and disseminated erythrocyte aggregation, a prolonged period of nuclide half-life in the intracutaneous depot. In the patients with calculous pyelonephritis in the remission phase shifts in the system of hemostasis were less noticeable, microcirculatory disorders were undetectable.
对52例慢性结石性肾盂肾炎患者的微循环状态和止血系统进行了长期研究。在手术前、术后2 - 4天、5 - 7天及出院时进行了调查。患者分为2组：处于炎症活动期的慢性肾盂肾炎患者和处于缓解期的慢性肾盂肾炎患者。在炎症活动期的结石性肾盂肾炎患者中，发现止血系统存在明显紊乱，其特征为纤维蛋白原血症、凝血酶血症、血浆肝素辅因子活性降低、血小板止血激活、CPa依赖性纤维蛋白溶解减少。这些变化与微循环系统紊乱同时出现：血流间歇性和弥散性红细胞聚集，皮内注射部位核素半衰期延长。在缓解期的结石性肾盂肾炎患者中，止血系统的变化不太明显，未检测到微循环紊乱。
