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干燥综合征中的慢性代偿性弥散性血管内凝血综合征

[Chronic compensated syndrome of disseminated intravascular coagulation in Sjögren's disease].

作者信息

Bezuglov M F, Ivanova A V, Rozanova L S

出版信息

Ter Arkh. 1988;60(12):89-91.

PMID:3247663
Abstract

The authors have reported the results of investigations of the system of hemostasis in 40 patients with Sjogren's disease (SD) and 30 healthy donors. The SD patients had different disorders of the system of hemostasis resulting in the activation of the coagulative and anticoagulative systems. Chronic compensated DIC syndrome was shown to be present in approximately half of the SD patients. A positive therapeutic effect of prednisolone combined with heparin on chronic DIC syndrome was shown. It was assumed that microcirculatory and blood coagulation disorders could play an important role in a pathological process.

摘要

作者报告了对40例干燥综合征(SD)患者和30名健康献血者止血系统的研究结果。SD患者存在不同的止血系统紊乱,导致凝血和抗凝系统激活。约一半的SD患者存在慢性代偿性弥散性血管内凝血(DIC)综合征。泼尼松龙联合肝素对慢性DIC综合征显示出积极的治疗效果。据推测,微循环和凝血障碍可能在病理过程中起重要作用。

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