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从新生儿动脉缺血性脑卒中后 7 年的早期运动能力到整体认知发育

From Early Motor Ability to Global Cognitive Development 7 Years after Neonatal Arterial Ischemic Stroke.

机构信息

INSERM, U1059 SAINBIOSE, Université Jean Monnet, Saint-Étienne, France.

Réanimation Néonatale, Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France.

出版信息

Dev Neurosci. 2024;46(3):149-152. doi: 10.1159/000533816. Epub 2023 Aug 30.

DOI:10.1159/000533816
PMID:37647866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11151956/
Abstract

The developmental condition of children after neonatal arterial ischemic stroke (NAIS) is characterized by cognitive and motor impairments. We hypothesized that independent walking age would be a predictor of later global cognitive functioning in this population. Sixty-one children with an available independent walking age and full-scale intelligence quotient (IQ) score 7 years after NAIS were included in this study. Full-scale IQ was assessed using the fourth edition of the Wechsler Intelligence Scale for Children (WISC-IV). Independent walking age was negatively correlated with full-scale IQ score at 7 years of age (Pearson correlation coefficient of -0.27; 95% confidence interval from -0.48 to -0.01; p < 0.05). Early motor function is correlated with later global cognitive functioning in children after NAIS. Assessing and promoting early motor ability is essential in this population.

摘要

新生儿动脉缺血性脑卒中(NAIS)后儿童的发育状况以认知和运动障碍为特征。我们假设独立行走年龄将是该人群日后整体认知功能的预测指标。本研究纳入了 61 名在 NAIS 后 7 年可获得独立行走年龄和全量表智商(IQ)评分的儿童。全量表 IQ 使用第四版韦氏儿童智力量表(WISC-IV)进行评估。独立行走年龄与 7 岁时的全量表 IQ 评分呈负相关(Pearson 相关系数为-0.27;95%置信区间为-0.48 至-0.01;p < 0.05)。新生儿动脉缺血性脑卒中后儿童的早期运动功能与日后的整体认知功能相关。在该人群中,评估和促进早期运动能力至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d210/11151956/b6b0212b710d/dne-2024-0046-0003-533816_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d210/11151956/b6b0212b710d/dne-2024-0046-0003-533816_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d210/11151956/b6b0212b710d/dne-2024-0046-0003-533816_F01.jpg

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Structural brain connectivity in children after neonatal stroke: A whole-brain fixel-based analysis.新生儿卒中后儿童的结构性脑连接:全脑基于固定元的分析。
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