编辑一个水稻 CDP-DAG 合酶赋予广谱抗性。

Editing a rice CDP-DAG synthase confers broad-spectrum resistance.

机构信息

State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

出版信息

Trends Plant Sci. 2023 Dec;28(12):1344-1346. doi: 10.1016/j.tplants.2023.08.011. Epub 2023 Aug 28.

DOI:10.1016/j.tplants.2023.08.011

PMID:37648632

Abstract

Lesion mimic mutations (LMMs) often confer broad-spectrum resistance (BSR) in plants, but with significant yield penalties. Sha et al. recently demonstrated that genome editing of the rice BSR gene RESISTANCE TO BLAST1 (RBL1), encoding a cytidine diphosphate diacylglycerol (CDP-DAG) synthase involved in phospholipid biosynthesis, confers multipathogen resistance without an obvious trade-off in yield.

摘要

损伤模拟突变（LMMs）通常在植物中赋予广谱抗性（BSR），但会导致显著的产量损失。Sha 等人最近证明，对编码参与磷脂生物合成的胞苷二磷酸二酰甘油（CDP-DAG）合酶的水稻 BSR 基因 RESISTANCE TO BLAST1（RBL1）进行基因组编辑，可赋予多种病原体抗性，而不会在产量上明显权衡。