Lee Hansongyi, Son Kumhee, Lee Inji, Lim Hyunjung
Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea.
Research Institute of Medical Nutrition, Kyung Hee University, Seoul, Korea.
J Obes Metab Syndr. 2023 Sep 30;32(3):269-278. doi: 10.7570/jomes23013. Epub 2023 Aug 31.
Menopause causes hormonal, physical, and psychological changes that are associated with an increase in risk of cardiovascular disease (CVD). This study examined the effects of medical nutrition therapy (MNT) on CVD risk factors in pre- and post-menopausal women with borderline dyslipidemia in Korea.
In total, 76 participants were divided into the MNT and control groups. MNT was performed for 12 weeks using intervention mapping with consideration of weight, blood lipid levels, and dietary assessment results. Anthropometric and biochemical measurements and dietary intake were analyzed.
The dietary energy and cholesterol intake, waist circumference (WC), blood triacylglycerol and very-low-density lipoprotein cholesterol levels, and atherogenic index (AI) of the pre-menopausal MNT group decreased significantly after the intervention. Moreover, dietary cholesterol intake, WC, waist-to-hip ratio, body fat percentage, total blood cholesterol, low-density lipoprotein to high-density lipoprotein ratio, and AI decreased significantly in the post-menopausal MNT group after the intervention.
MNT for 12 weeks is effective in decreasing risk factors associated with CVD in Korean women with borderline dyslipidemia, and the effects differ between pre- and post-menopausal women.
更年期会引发激素、身体和心理变化,这些变化与心血管疾病(CVD)风险增加相关。本研究探讨了医学营养治疗(MNT)对韩国血脂临界异常的绝经前和绝经后女性心血管疾病风险因素的影响。
总共76名参与者被分为MNT组和对照组。根据体重、血脂水平和饮食评估结果,采用干预映射法进行了为期12周的MNT。对人体测量和生化指标以及饮食摄入量进行了分析。
干预后,绝经前MNT组的饮食能量和胆固醇摄入量、腰围(WC)、血液甘油三酯和极低密度脂蛋白胆固醇水平以及致动脉粥样硬化指数(AI)显著降低。此外,干预后绝经后MNT组的饮食胆固醇摄入量、WC、腰臀比、体脂百分比、总血胆固醇、低密度脂蛋白与高密度脂蛋白比值以及AI均显著降低。
为期12周的MNT可有效降低韩国血脂临界异常女性与心血管疾病相关的风险因素,且绝经前和绝经后女性的效果有所不同。