Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Cleft Palate Craniofac J. 2025 Jan;62(1):44-50. doi: 10.1177/10556656231198647. Epub 2023 Aug 30.
To compare patient-reported outcomes (PROs) in internationally adopted patients with cleft lip and palate to those in non-adopted peers.
Cross-sectional study.
Multidisciplinary cleft team at tertiary care hospital.
Patients aged ≥ 8 with cleft lip and palate attending routine cleft team evaluations September 2021 - September 2022.
CLEFT-Q PRO scores.
Sixty-four internationally adopted patients and 113 non-adopted patients with a mean age of 13 years were included. Compared to non-adopted peers, adopted patients demonstrated worse satisfaction with face appearance (mean 59 vs. 66, = .044), speech function (mean 69 vs. 78, = .005), and speech distress (mean 80 vs. 84, = .032). No significant differences were observed on the nose, nostrils, teeth, lips, lip scar, jaws, psychological function, or social function scales (> .05). Objective clinical evaluation corroborated these findings, with adopted patients demonstrating worse Pittsburgh Weighted Speech scores (mean 3.0 vs 1.9, = .027) and greater incidence of articulation errors (64% vs 46%, = .021). No significant differences were observed in rates of mood, anxiety, or behavior concerns identified on psychosocial assessment ( = .764). Among adopted patients, undergoing palatoplasty prior to adoption was associated with worse satisfaction with speech, appearance, school, and social function (< .05).
Patient-reported outcomes among internationally adopted adolescents and young adults with cleft lip and palate show slightly lower satisfaction with facial appearance and speech but otherwise demonstrate similar results to non-adopted peers on most appearance and psychosocial measures. PRO data correlated well with objective speech assessment and did not portend worse psychosocial function.
比较国际收养唇腭裂患者与非收养同龄人患者报告的结局（PROs）。
横断面研究。
三级保健医院多学科腭裂团队。
2021 年 9 月至 2022 年 9 月期间，年龄≥8 岁、接受常规腭裂团队评估的唇腭裂患者。
CLEFT-Q PRO 评分。
纳入 64 名国际收养患者和 113 名非收养患者，平均年龄为 13 岁。与非收养同龄人相比，收养患者的面部外观满意度（平均 59 分 vs. 66 分，=0.044）、言语功能（平均 69 分 vs. 78 分，=0.005）和言语困扰（平均 80 分 vs. 84 分，=0.032）较差。在鼻子、鼻孔、牙齿、嘴唇、唇瘢痕、颌骨、心理功能或社会功能量表上未观察到显著差异（>0.05）。客观临床评估证实了这些发现，收养患者的匹兹堡语音重量评分（平均 3.0 分 vs. 1.9 分，=0.027）更差，构音错误发生率更高（64% vs. 46%，=0.021）。在社会心理评估中，情绪、焦虑或行为问题的发生率无显著差异（=0.764）。在收养患者中，在收养前接受腭裂手术与言语、外貌、学校和社会功能满意度较差相关（<0.05）。
国际收养的唇腭裂青少年和年轻成人患者的患者报告结局显示，他们对面部外观和言语的满意度略低，但在大多数外观和社会心理测量上与非收养同龄人相比结果相似。PRO 数据与客观言语评估相关性良好，且不会导致更差的社会心理功能。
