Stroke. 1986 Sep-Oct;17(5):848-52. doi: 10.1161/01.str.17.5.848.
An objective, retrospective review of 358 carotid endarterectomies performed in the neurosurgical teaching units of the University of Toronto in the year 1982 demonstrated a perioperative stroke rate of 3.9% and a death rate of 1.5%. Most (82%) surgical neurological complications occurred after the immediate post-operative period (24 hours). This high incidence of delayed stroke suggests that most perioperative strokes are embolic rather than hemodynamic. Careful operative technique and the use of anticoagulants and antiplatelet agents may be more important in preventing postoperative deficits than intraoperative monitoring and intraluminal shunting. Our figures and those of current published data indicate that a 5-6% combined morbidity and mortality should be expected in carotid endarterectomy. These data are critical both to decision making with the individual patient as well as in the planning of future carotid surgery trials.
对1982年在多伦多大学神经外科教学单位进行的358例颈动脉内膜切除术进行的一项客观回顾性研究表明，围手术期卒中发生率为3.9%，死亡率为1.5%。大多数（82%）手术神经并发症发生在术后即刻（24小时）之后。这种延迟性卒中的高发生率表明，大多数围手术期卒中是栓塞性的而非血流动力学性的。与术中监测和腔内分流相比，仔细的手术技术以及抗凝剂和抗血小板药物的使用在预防术后神经功能缺损方面可能更为重要。我们的数据以及当前已发表的数据表明，颈动脉内膜切除术的合并发病率和死亡率预计应为5-6%。这些数据对于个体患者的决策以及未来颈动脉手术试验的规划都至关重要。
