Khalkhali Mohammadrasoul, Rasekh Kiarash, Eslamdoust-Siahestalkhi Fatemeh, Farrahi Hassan, Zare Roghaye
Kavosh Cognitive Behavior Sciences and Addiction Research Center, Department of Psychiatry, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Neuroscience Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Front Psychiatry. 2023 Aug 15;14:1164750. doi: 10.3389/fpsyt.2023.1164750. eCollection 2023.
Metabolic syndrome (MetS) is a collection of chemical and clinical risk factors. Patients with obsessive-compulsive disorder (OCD) might be at risk of MetS. This study aimed to investigate the prevalence and clinical correlates of MetS in an Iranian clinical sample of patients with OCD.
We included 107 patients with OCD in a cross-sectional study. Demographic and clinical characteristics including OC symptoms, duration of treatment, age of onset, medications history, and comorbidity with other psychiatric disorders were collected.
The prevalence of MetS was 39.2%. Abdominal obesity was the most frequent component of MetS (68.2%), followed by low high-density lipoprotein cholesterol (50.5%). High serum triglycerides, high fasting serum glucose, high systolic blood pressure, and high diastolic blood pressure were observed in 47.7, 20.6, 18.7, and 9.3% of patients, respectively. Patients with MetS were older, married, had a low education level, had a high body mass index, and had no aggressive OC symptoms. MetS was not associated with psychiatric disorders comorbidities, age of onset, and duration of treatment.
The results of this study were in line with the results of other studies that reported the poor health status of patients with OCD. A large number of patients are affected or are at risk of developing MetS. These patients need medical care along with the usual OCD treatments.
代谢综合征（MetS）是一系列化学和临床风险因素的集合。强迫症（OCD）患者可能有患代谢综合征的风险。本研究旨在调查伊朗强迫症患者临床样本中代谢综合征的患病率及其临床相关因素。
我们纳入了107例强迫症患者进行横断面研究。收集了人口统计学和临床特征，包括强迫症状、治疗持续时间、发病年龄、用药史以及与其他精神障碍的共病情况。
代谢综合征的患病率为39.2%。腹型肥胖是代谢综合征最常见的组成部分（68.2%），其次是高密度脂蛋白胆固醇水平低（50.5%）。分别有47.7%、20.6%、18.7%和9.3%的患者存在高血清甘油三酯、高空腹血糖、高收缩压和高舒张压。患有代谢综合征的患者年龄较大、已婚、教育水平低、体重指数高且没有攻击性强迫症状。代谢综合征与精神障碍共病、发病年龄和治疗持续时间无关。
本研究结果与其他报道强迫症患者健康状况不佳的研究结果一致。大量患者受到影响或有患代谢综合征的风险。这些患者在接受常规强迫症治疗的同时还需要医疗护理。
