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醋酸格拉替雷致药物性肝损伤并导致肝移植:一例报告

Drug-induced liver injury by glatiramer acetate leading to liver transplant: A case report.

作者信息

Amirkhani Nikan, Khalaji Amirmohammad, Alehossein Parsa, Safaei Masoomeh, Aletaha Najme, Miroliaee Arash

机构信息

School of Medicine Tehran University of Medical Sciences Tehran Iran.

Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran Iran.

出版信息

JGH Open. 2023 Jul 26;7(8):591-593. doi: 10.1002/jgh3.12938. eCollection 2023 Aug.

Abstract

Glatiramer acetate (GA) is a widely used immune-modulating drug in relapsing multiple sclerosis (MS). Although a few cases of drug-induced liver injury during GA therapy have been reported earlier, herein we present the case of a 43-year-old woman with relapsing MS who experienced acute liver failure after GA therapy, ultimately leading to liver transplant.

摘要

醋酸格拉替雷(GA)是复发型多发性硬化症(MS)中广泛使用的免疫调节药物。尽管此前已有一些关于GA治疗期间药物性肝损伤的病例报道,但在此我们报告一例43岁复发型MS女性患者,其在接受GA治疗后发生急性肝衰竭,最终接受了肝移植。

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