Abu Sabha Mosa R, Bairmani Zinah A, Alfroukh Khadeejeh M, Nassar Osayd, Albakri Mutaz
Internal Medicine, Faculty of Medicine, Al Quds University, Jerusalem, PSE.
Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, USA.
Cureus. 2023 Jul 30;15(7):e42690. doi: 10.7759/cureus.42690. eCollection 2023 Jul.
Congenital malformations of the inferior vena cava (IVC) are rare and often asymptomatic, typically discovered incidentally during imaging. However, these anomalies can result in circulatory stasis, impede venous return, and serve as predisposing factors for thrombus formation. Here, we present a unique case of a 28-year-old female patient who was found to have interrupted IVC with azygos continuation, an exceedingly rare IVC anomaly, during a work-up of extensive bilateral deep vein thrombosis (DVT) with an intraabdominal extension which was triggered by recent combined oral contraceptive pills (OCP) use. This case highlights the importance of considering vena cava malformations as an underlying cause for extensive DVT, even in the absence of conventional risk factors. Clinicians should be aware of the potential association between congenital vena cava anomalies and thrombotic events, as early recognition and appropriate management are crucial for preventing complications such as pulmonary embolism.
下腔静脉（IVC）先天性畸形较为罕见，通常无症状，多在影像学检查时偶然发现。然而，这些异常可导致循环淤滞，阻碍静脉回流，并成为血栓形成的诱发因素。在此，我们报告一例独特病例，一名28岁女性患者，在因近期服用复方口服避孕药（OCP）引发广泛双侧下肢深静脉血栓形成（DVT）并累及腹腔进行检查时，发现存在下腔静脉中断并奇静脉延续这一极其罕见的下腔静脉异常情况。该病例强调了即便没有传统危险因素，也需考虑腔静脉畸形作为广泛DVT潜在病因的重要性。临床医生应意识到先天性腔静脉异常与血栓形成事件之间的潜在关联，因为早期识别和恰当处理对于预防肺栓塞等并发症至关重要。
