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用于生物医学应用的 PET 复丝纺织品的表面处理:粗糙度改性和成纤维细胞活力评估。

Surface treatment of PET multifilament textile for biomedical applications: roughness modification and fibroblast viability assessment.

机构信息

Laboratoire de Génie Textile (LGTex), Ksar-Hellal, Tunisia.

Laboratoire de Physique et Mécanique Textiles (LPMT), ENSISA, Mulhouse, France.

出版信息

Biomed Tech (Berl). 2023 Sep 1;69(1):17-26. doi: 10.1515/bmt-2023-0221. Print 2024 Feb 26.

Abstract

OBJECTIVES

The aim of this study was to investigate the potential of tuning the topography of textile surfaces for biomedical applications towards modified cell-substrate interactions.

METHODS

For that purpose, a supercritical Nitrogen N jet was used to spray glass particles on multi-filament polyethylene terephthalate (PET) yarns and on woven fabrics. The influence of the jet projection parameters such as the jet pressure (P) and the standoff distance (SoD) on the roughness was investigated.

RESULTS

The impact of the particles created local filament ruptures on the treated surfaces towards hairiness increase. The results show that the treatment increases the roughness by up to 17 % at P 300 bars and SoD 300 mm while the strength of the material is slightly decreased. The biological study brings out that proliferation can be slightly limited on a more hairy surface, and is increased when the surface is more flat. After 10 days of fibroblast culture, the cells covered the entire surface of the fabrics and had mainly grown unidirectionally, forming cell clusters oriented along the longitudinal axis of the textile yarns. Clusters were generated at yarn crossings.

CONCLUSIONS

This approach revealed that the particle projection technology can help tuning the cell proliferation on a textile surface.

摘要

目的

本研究旨在探讨通过调整纺织表面形貌来实现对生物医学应用的调控,以改变细胞与基底的相互作用。

方法

为此,我们使用超临界氮气射流将玻璃颗粒喷射到多丝聚酯(PET)纱线和机织物上。研究了射流喷射参数,如射流压力(P)和喷距(SoD)对粗糙度的影响。

结果

颗粒的冲击在处理表面上产生了局部纤维断裂,导致绒毛增加。结果表明,在 P 为 300 巴和 SoD 为 300 毫米时,处理可将粗糙度提高高达 17%,而材料的强度略有降低。生物学研究表明,在更粗糙的表面上增殖可能会受到轻微限制,而在更平整的表面上增殖会增加。在成纤维细胞培养 10 天后,细胞覆盖了织物的整个表面,并主要沿纺织纱线的纵轴单向生长,形成沿纱线交叉点取向的细胞簇。

结论

该方法表明,颗粒喷射技术可以帮助调整纺织表面的细胞增殖。

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