Department of Health Promotion and Behavioral Sciences, UTHealth School of Public Health, Houston, TX, USA.
Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
JNCI Cancer Spectr. 2023 Aug 31;7(5). doi: 10.1093/jncics/pkad065.
Human papillomavirus (HPV) vaccination among adolescents has steadily improved over the past several years. However, research conducted to determine whether the COVID-19 pandemic disrupted this positive trend in HPV vaccine initiation among racial and ethnic minority adolescents is limited. Therefore, this study was conducted to determine if the COVID-19 pandemic and the resulting changes in the US health-care sector affected the increasing HPV vaccine initiation among non-Hispanic Black and Hispanic adolescents aged 13-17 years.
Using a cross-sectional design to examine data from the National Immunization Survey-Teen (2019-2021), logistic regression and moderation analysis were used to model race-specific variations in HPV vaccine initiation (n = 49 031). Two-sided P values of up to .05 were considered statistically significant.
Hispanic (adjusted odds ratio [AOR] = 1.35, 95% confidence interval [CI] = 1.16 to 1.57) and non-Hispanic Black (AOR = 1.29, 95% CI = 1.10 to 1.51) adolescents had higher odds of HPV vaccine initiation than did non-Hispanic White adolescents. Additionally, the odds of HPV vaccine initiation were higher in 2021 (AOR = 1.22, 95% CI = 1.08 to 1.38) than in 2019. Other variables-age, region, sex, insurance status, and poverty status-were also associated with HPV vaccine initiation.
These findings demonstrate that during the COVID-19 pandemic, racial and ethnic minorities had higher odds of receiving the HPV vaccine. Therefore, more research of the impact of the pandemic on HPV vaccine initiation among non-Hispanic White and racial and ethnic minority adolescents is needed.
在过去几年中,青少年人乳头瘤病毒(HPV)疫苗接种率稳步提高。然而,关于 COVID-19 大流行是否破坏了少数族裔青少年 HPV 疫苗接种启动这一积极趋势的研究有限。因此,本研究旨在确定 COVID-19 大流行及其对美国医疗保健部门的影响是否影响了 13-17 岁非西班牙裔黑人和西班牙裔青少年 HPV 疫苗接种率的增加。
本研究使用横断面设计,分析了全国免疫调查-青少年(2019-2021 年)的数据,采用逻辑回归和调节分析模型,对 HPV 疫苗接种启动的种族特异性差异进行建模(n=49031)。双侧 P 值达到 0.05 被认为具有统计学意义。
西班牙裔(调整后的优势比 [AOR]=1.35,95%置信区间 [CI]=1.16-1.57)和非西班牙裔黑人(AOR=1.29,95%CI=1.10-1.51)青少年 HPV 疫苗接种启动的几率高于非西班牙裔白人青少年。此外,2021 年 HPV 疫苗接种启动的几率高于 2019 年(AOR=1.22,95%CI=1.08-1.38)。其他变量,如年龄、地区、性别、保险状况和贫困状况,也与 HPV 疫苗接种启动相关。
这些发现表明,在 COVID-19 大流行期间,少数族裔青少年接种 HPV 疫苗的几率更高。因此,需要更多研究大流行对非西班牙裔白人和少数族裔青少年 HPV 疫苗接种启动的影响。