Toh Zheng Quan, Russell Fiona M, Garland Suzanne M, Mulholland Edward K, Patton George, Licciardi Paul V
Infection and Immunity, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.
JNCI Cancer Spectr. 2021 Mar 2;5(2):pkab011. doi: 10.1093/jncics/pkab011. eCollection 2021 Apr.
The current global novel coronavirus disease 2019 (COVID-19) pandemic threatens to derail the uptake of human papillomavirus (HPV) vaccination in low- and lower-middle income countries with major disruptions to routine immunization and the introduction of new vaccines delayed. This has a major impact on the World Health Organization cervical cancer elimination strategy, where it is dependent on HPV vaccination as well as cervical cancer screening and treatment. We discuss current opportunities and barriers to achieve high uptake of HPV vaccination in low- and lower-middle income countries as well as the impact of COVID-19. Implementation of 4 key recommendations for HPV vaccination in low- and lower-middle income countries is needed: increased global financial investment; improved vaccine supply and accelerated use of a single-dose schedule; education and social marketing; and adoption of universal school-based delivery. With the commitment of the global health community, the adoption of these strategies would underpin the effective elimination of cervical cancer.
当前全球2019年新型冠状病毒病(COVID-19)大流行可能会使低收入和中低收入国家的人乳头瘤病毒(HPV)疫苗接种工作脱轨,常规免疫受到重大干扰,新疫苗的引进也被推迟。这对世界卫生组织的宫颈癌消除战略产生了重大影响,该战略依赖于HPV疫苗接种以及宫颈癌筛查和治疗。我们讨论了在低收入和中低收入国家实现HPV疫苗高接种率的当前机遇和障碍,以及COVID-19的影响。在低收入和中低收入国家实施HPV疫苗接种的4项关键建议是必要的:增加全球财政投资;改善疫苗供应并加速使用单剂次接种方案;开展教育和社会营销;采用基于学校的普遍接种方式。在全球卫生界的共同努力下,采用这些策略将为有效消除宫颈癌奠定基础。