Alshammari Ayed, Gattan Hattan S, Marzok Mohamed, Salem Mohamed, Al-Jabr Omar A, Selim Abdelfattah
Department of Biology, College of Science, University of Hafr Al-Batin, Hafr Al-Batin, Saudi Arabia.
Special Infectious Agents Unit, King Fahad Medical Research Center, King AbdulAziz University, Jeddah, Saudi Arabia; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
J Equine Vet Sci. 2023 Nov;130:104915. doi: 10.1016/j.jevs.2023.104915. Epub 2023 Aug 29.
Fasciola hepatica is a trematode parasite that affects wide range of mammalian hosts including horses. There are no epidemiological data on fasciolosis in Egyptian horses. Hence, the present study aimed to evaluate the seroprevalence of F. hepatica in horses using ELISA as well as assess the associated risk factors for fasciolosis infection. A total of 400 sera samples of horses from three Egyptian governorates were examined. The overall seroprevalence rate in horses was 13% and the disease was more prevalent in Qalubia (14.17%) and Gharbia (16.67%) which are located at Nile Delta. The likelihood of having F. hepatica seropositivity was higher in mixed-breed animals and stallions (OR = 3.97, 95%CI: 1.10-14.28 and OR = 2.07, 95%CI: 1.09-3.93, respectively), and in older horses more than 10 years (OR = 5.69, 95% CI: 1.98-16.36). Horses were more likely to be seropositive with F. hepatica when kept in outdoor housing (OR= 1.53, 95%CI: 0.78-3), during autumn (OR = 3.80, 95%CI: 1.17-12.32) and in the presence of snails (OR = 2.72, 95%CI: 1.34-5.52). Therefore, the obtained data contributes to the understanding of the epidemiology of Fasciola species, assess in establishment of management programmes to reduce disease and public health risks.
肝片吸虫是一种吸虫寄生虫，可感染包括马在内的多种哺乳动物宿主。埃及马匹中尚无关于肝片吸虫病的流行病学数据。因此，本研究旨在使用酶联免疫吸附测定（ELISA）评估马肝片吸虫的血清阳性率，并评估肝片吸虫病感染的相关危险因素。对来自埃及三个省份的400份马血清样本进行了检测。马匹的总体血清阳性率为13%，该病在位于尼罗河三角洲的盖勒尤比省（14.17%）和加比亚省（16.67%）更为普遍。杂种动物和种马感染肝片吸虫血清阳性的可能性更高（比值比分别为3.97，95%置信区间：1.10 - 14.28和2.07，95%置信区间：1.09 - 3.93），10岁以上的老马也是如此（比值比为5.69，95%置信区间：1.98 - 16.36）。当马匹饲养在室外（比值比 = 1.53，95%置信区间：0.78 - 3）、秋季（比值比 = 3.80，95%置信区间：1.17 - 12.32）以及有蜗牛存在的环境中（比值比 = 2.72，95%置信区间：1.34 - 5.52）时，感染肝片吸虫血清阳性的可能性更大。因此，所获得的数据有助于了解肝片吸虫属的流行病学，为制定减少疾病和公共卫生风险的管理计划提供评估依据。
