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化脓性汗腺炎的评估工具和表型分类。

Assessment tools and phenotype classification for hidradenitis suppurativa.

机构信息

Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

出版信息

Clin Dermatol. 2023 Sep-Oct;41(5):601-610. doi: 10.1016/j.clindermatol.2023.08.016. Epub 2023 Aug 29.

DOI:10.1016/j.clindermatol.2023.08.016
PMID:37652190
Abstract

Hidradenitis suppurativa (HS) is a heterogeneous chronic relapsing skin disease. Several assessment tools are used to assess disease severity and to classify disease phenotype; however, no consensus exists. This review evaluates the various assessment tools and phenotypes, assessing their validity and reliability. Numerous assessment tools and phenotype classifications have been proposed for identifying various subtypes within the hidradenitis suppurativa disease spectrum. Each has a different purpose, such as use in daily practice or in clinical trial settings. Several assessment tools and phenotype classifications have been validated but not always with satisfactory results and often with studies showing divergent intra-rater reliability results. A consensus is needed for a validated, easy-to-use, and timesaving assessment tool for routine daily practice. For clinical trials, a validated and extensive assessment tool that also measures response to treatment is also needed.

摘要

化脓性汗腺炎(HS)是一种异质性的慢性复发性皮肤病。有几种评估工具用于评估疾病严重程度和分类疾病表型;然而,目前尚未达成共识。本综述评估了各种评估工具和表型,评估了它们的有效性和可靠性。已经提出了许多评估工具和表型分类,以识别化脓性汗腺炎疾病谱中的各种亚型。每种工具都有不同的用途,例如在日常实践或临床试验环境中使用。已经验证了几种评估工具和表型分类,但并非总是如此,结果令人满意,而且经常有研究显示出不同的内部评估者可靠性结果。需要达成共识,制定一种经过验证、易于使用且节省时间的评估工具,用于日常实践。对于临床试验,还需要一种经过验证的、广泛的评估工具,该工具还可以衡量对治疗的反应。

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