Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Department of Dermatology, Roskilde Hospital, Health Sciences Faculty, University of Copenhagen, Roskilde, Denmark.
J Am Acad Dermatol. 2015 Nov;73(5 Suppl 1):S23-6. doi: 10.1016/j.jaad.2015.07.047.
Current classifications for hidradenitis suppurativa (HS), such as the Hurley staging system, are not very specific. The absence of rigorous classifications is incongruous with the clinical variability of the condition. There is no pathognomonic sign for HS that leads to a diagnosis that is unquestionable. Consequently, diagnosis is made largely through clinical presentation of the condition. The use of several validated tools assists in confirming the diagnosis and the severity of the disease. In future investigations, the identification of phenotypes and clinical subtypes--taking into account genetic variants--will serve to identify subpopulations of patients who are responsive to particular therapies, thereby improving the overall therapeutic picture for patients with HS. There is a potential for personalized, tailored delivery of therapy in the HS setting.
目前用于化脓性汗腺炎 (HS) 的分类方法，如 Hurley 分期系统，不是很具体。缺乏严格的分类与该病的临床变异性不一致。HS 没有明确的特征性标志导致诊断不可置疑。因此，诊断主要通过疾病的临床表现进行。使用几种经过验证的工具有助于确认诊断和疾病的严重程度。在未来的研究中，通过考虑遗传变异，确定表型和临床亚型将有助于识别对特定治疗有反应的患者亚群，从而改善 HS 患者的整体治疗情况。在 HS 治疗中，有可能实现个性化、定制化的治疗方案。
