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老年人癌症评估:政策建议。

Geriatric assessment for older people with cancer: policy recommendations.

机构信息

Department of Geriatric Medicine, Diakonessenhuis, 3582 KE, Utrecht, The Netherlands.

Department of Medicine, University Health Network, Toronto, ON, M5G 2C4, Canada.

出版信息

Glob Health Res Policy. 2023 Sep 1;8(1):37. doi: 10.1186/s41256-023-00323-0.

Abstract

Most cancers occur in older people and the burden in this age group is increasing. Over the past two decades the evidence on how best to treat this population has increased rapidly. However, implementation of new best practices has been slow and needs involvement of policymakers. This perspective paper explains why older people with cancer have different needs than the wider population. An overview is given of the recommended approach for older people with cancer and its benefits on clinical outcomes and cost-effectiveness. In older patients, the geriatric assessment (GA) is the gold standard to measure level of fitness and to determine treatment tolerability. The GA, with multiple domains of physical health, functional status, psychological health and socio-environmental factors, prevents initiation of inappropriate oncologic treatment and recommends geriatric interventions to optimize the patient's general health and thus resilience for receiving treatments. Multiple studies have proven its benefits such as reduced toxicity, better quality of life, better patient-centred communication and lower healthcare use. Although GA might require investment of time and resources, this is relatively small compared to the improved outcomes, possible cost-savings and compared to the large cost of oncologic treatments as a whole.

摘要

大多数癌症发生在老年人中,且该年龄段的负担正在增加。在过去的二十年中,关于如何最好地治疗这一人群的证据迅速增加。然而,新最佳实践的实施一直很缓慢,需要政策制定者的参与。本文从为什么癌症患者比一般人群有不同的需求的角度来解释这一问题。本文概述了针对癌症老年患者的推荐方法,以及其对临床结果和成本效益的益处。在老年患者中,老年综合评估(GA)是衡量健康水平和确定治疗耐受性的金标准。GA 涵盖了多个领域,包括身体健康、功能状态、心理健康和社会环境因素,可以防止不适当的肿瘤治疗的启动,并建议进行老年干预以优化患者的整体健康状况,从而提高对治疗的适应能力。多项研究已经证明了其益处,例如降低毒性、提高生活质量、更好的以患者为中心的沟通以及降低医疗保健的使用。尽管 GA 可能需要投入时间和资源,但与改善结果、可能的节省成本以及整个肿瘤治疗的巨大成本相比,这相对较小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3541/10472678/abab9a112c1e/41256_2023_323_Fig1_HTML.jpg

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