甲状腺孤立性纤维瘤 1 例报告并文献复习
A case report of solitary fibrous tumor of the thyroid gland and literature review.
机构信息
Clinical Medical College of Jining Medical University, Jining, People's Republic of China.
Department of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of Jining Medical University, Jining, People's Republic of China.
出版信息
Medicine (Baltimore). 2023 Aug 25;102(34):e34710. doi: 10.1097/MD.0000000000034710.
RATIONALE
A solitary fibrous tumor (SFT) is an uncommon soft tissue tumor that was first discovered in the pleura. Although SFTs have been documented in other extra-pleural sites, an SFT in the thyroid gland is highly unusual. An SFT of the thyroid gland can be difficult to diagnose, and there is little information about their Underlying biological behavior.
PATIENT CONCERNS
We present a case of a 63-year-old man with a progressively growing left-neck mass detected 1 month ago, which was pathologically confirmed to be a benign SFT of the thyroid gland.
DIAGNOSIS
Postoperative pathological examination of the tumor revealed an SFT. Immunopathological examination was consistent with the diagnosis of an SFT.
INTERVENTIONS
The patient underwent surgical resection of the SFT.
OUTCOMES
The patient was recurrence-free during 1.5 years of follow-up.
LESSONS
Surgical excision is beneficial in SFTs that show no histological signs of malignancy, such as pleomorphism, enhanced mitotic activity, necrosis, bleeding, or capsular invasion. However, because the biologic activity remains unknown, meticulous long-term monitoring is required.
背景
孤立性纤维瘤（SFT）是一种罕见的软组织肿瘤，最初发现于胸膜。虽然 SFT 已在其他胸膜外部位被记录，但甲状腺中的 SFT 非常罕见。甲状腺 SFT 难以诊断，关于其潜在生物学行为的信息很少。
病例报告
我们报告了 1 个月前发现的 1 例 63 岁男性患者，其左颈部逐渐增大的肿块，病理证实为甲状腺良性 SFT。
诊断
肿瘤的术后病理检查显示为 SFT。免疫病理学检查符合 SFT 的诊断。
干预措施
患者接受了 SFT 的手术切除。
结果
患者在 1.5 年的随访中无复发。
结论
对于没有组织学恶性迹象的 SFT（如多形性、有丝分裂活性增强、坏死、出血或包膜侵犯），手术切除是有益的。然而，由于其生物学活性尚不清楚，需要进行细致的长期监测。
Zotero 插件