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超声检查对HIV和艾滋病患者腹部病变的检测及其与CD4细胞计数的相关性——一项原创研究

Assessment of the USG Detection of Abdominal Pathologies in HIV and Aids and its Association with CD4 Counts - An Original Research.

作者信息

Kyasa Sai V, Achuta Kesava M, Gupta Manoj K, Ajmeera Rajunaik, Kancherla Neeraj, Singh Faziljot

机构信息

Department of Radio-Diagnosis, Chettinad Health City, Chennai, India.

Department of Internal Medicine, King George Hospital, Visakhapatnam, Andhra Pradesh, India.

出版信息

J Pharm Bioallied Sci. 2023 Jul;15(Suppl 1):S262-S267. doi: 10.4103/jpbs.jpbs_461_22. Epub 2023 Jul 5.

Abstract

INTRODUCTION

In individuals with acquired immunodeficiency syndrome (HIV/AIDS), abdominal pathologies rank second in frequency only to pulmonary illnesses. An essential imaging method for assessing abdominal diseases is ultrasonography (USG). In this study, abdominal pathologies in HIV/AIDS patients were evaluated using USG, and their relationship to CD4 count was further examined.

MATERIALS AND TECHNIQUES

400 HIV+ subjects with aberrant abdominal USG participated in the current investigation. The subjects were assessed and graded as per the CD4 counts. Later the comparisons were drawn between the USG, and its relationship to CD4 count using SPSS 16.0 software, and all data were examined using appropriate statistical tools.

RESULTS

Men were over 60% of the 400 subjects. The average age of these subjects was 35.6 years; the range for this age group was 6 to 63 years. Spleen involvement was found on ultrasonographic examination in 45.1% of subjects, while liver and lymph node involvement was seen in 43.6% of subjects. Substantial correlations between CD4 counts and findings such as periportal & mesenteric lymphadenopathy, localized pancreatic lesion, splenic microabscess, splenomegaly, and hepatomegaly were found. One percent of individuals had lymphoma, which affected the retroperitoneal lymph nodes, pancreas, and liver.

CONCLUSION

Present research demonstrates the significance of abdominal ultrasonographic examination in HIV+ patients. CD4 counts have a big impact on how an HIV/AIDS patient's differential diagnosis is determined. The interpretation of USG results in relation to CD4 levels may aid in accurate diagnosis.

摘要

引言

在获得性免疫缺陷综合征(HIV/AIDS)患者中,腹部病变的发生率仅次于肺部疾病,位居第二。超声检查(USG)是评估腹部疾病的一种重要影像学方法。在本研究中,我们使用超声检查评估了HIV/AIDS患者的腹部病变,并进一步研究了这些病变与CD4细胞计数的关系。

材料与方法

400例腹部超声检查异常的HIV阳性受试者参与了本研究。根据CD4细胞计数对受试者进行评估和分级。随后,使用SPSS 16.0软件对超声检查结果及其与CD4细胞计数的关系进行比较,并使用适当的统计工具对所有数据进行分析。

结果

400名受试者中男性占比超过60%。这些受试者的平均年龄为35.6岁,年龄范围为6至63岁。超声检查发现45.1%的受试者脾脏受累,43.6%的受试者肝脏和淋巴结受累。发现CD4细胞计数与门周及肠系膜淋巴结肿大、局限性胰腺病变、脾微脓肿、脾肿大和肝肿大等表现之间存在显著相关性。1%的个体患有淋巴瘤,累及腹膜后淋巴结、胰腺和肝脏。

结论

本研究表明腹部超声检查在HIV阳性患者中的重要性。CD4细胞计数对HIV/AIDS患者的鉴别诊断有很大影响。结合CD4水平解读超声检查结果可能有助于准确诊断。

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