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播散性光化性肉芽肿病例报告:一种异常广泛的表现形式。

A report of disseminated actinic granuloma: An unusually extensive presentation.

作者信息

Ahlers Carolyn, Parker Eva Rawlings

机构信息

Department of Medicine, Duke University School of Medicine, Durham, NC, USA.

Department of Dermatology, Vanderbilt University Medical Center, Nashville, TN, USA.

出版信息

SAGE Open Med Case Rep. 2023 Aug 25;11:2050313X231195487. doi: 10.1177/2050313X231195487. eCollection 2023.

Abstract

In this report, a case of disseminated actinic granuloma in a 50-year-old female with type 2 diabetes mellitus is described. This case is unique due to the unusually extensive cutaneous involvement of the face, neck, trunk, and extremities at initial presentation. The lesions were in a striking photo-distribution, highlighting ultraviolet light as an important environmental trigger for this process. Interestingly, the patient refused the recommended systemic therapy with hydroxychloroquine, despite her significant burden of skin disease. This refusal stems from an unexpected reluctance on the part of the patient to take this medication due to the publicity and media coverage of side effects associated with inappropriate prescribing of this drug during the COVID-19 pandemic, presenting a new and surprising treatment barrier that clinicians may need to overcome.

摘要

在本报告中,描述了一例50岁2型糖尿病女性的播散性光化性肉芽肿病例。该病例具有独特性,因为在初次就诊时面部、颈部、躯干和四肢出现了异常广泛的皮肤受累。病变呈显著的光分布,突出了紫外线作为这一过程的重要环境触发因素。有趣的是,尽管该患者有严重的皮肤疾病负担,但她拒绝了推荐的羟氯喹系统治疗。这种拒绝源于患者出乎意料的不情愿服用此药,原因是在新冠疫情期间该药物不当处方相关副作用的宣传和媒体报道,这呈现出一种临床医生可能需要克服的新的、令人惊讶的治疗障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cc0/10467196/48daf2ae1728/10.1177_2050313X231195487-fig1.jpg

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