Revenga F, Rovira I, Pimentel J, Alejo M
Unit of Dermatology, Hospital Universitario Infanta Cristina, Badajoz, Spain.
Clin Exp Dermatol. 1996 Jan;21(1):51-3.
A 56-year-old woman with annular elastolytic giant cell granuloma is reported. She had annular, slowly growing lesions on sun-exposed areas and the dorsum of one foot. Biopsies from both areas revealed a mid-dermal inflammatory infiltrate with many giant cells engulfing elastic fibres. The current nosological situation of this process is discussed. Actinic granuloma (AG) is a term coined by O'Brien in 1975 to describe a cutaneous process characterized by multiple annular lesions located on sun-exposed skin areas. The histopathology is defined by the presence of multinucleated giant cells containing elastic fibres at the lesion edge, and the absence of these fibres at the lesion centre. The nosology of this disease and the role of actinic exposure as a triggering factor for it has been much discussed in recent years. We report a new case of AG not limited to photo-exposed areas.
报道了一名56岁患有环状弹性组织溶解性巨细胞肉芽肿的女性。她在暴露于阳光的部位和一只脚的背部有环状、生长缓慢的皮损。这两个部位的活检均显示真皮中层有炎症浸润,有许多巨细胞吞噬弹性纤维。讨论了该病程目前的疾病分类情况。光化性肉芽肿(AG)是奥布赖恩在1975年创造的一个术语,用于描述一种以位于暴露于阳光的皮肤区域的多个环状皮损为特征的皮肤病变。组织病理学表现为病变边缘存在含有弹性纤维的多核巨细胞,而病变中心则无这些纤维。近年来,关于这种疾病的分类学以及光化暴露作为其触发因素的作用一直备受讨论。我们报告了一例不限于光暴露部位的AG新病例。