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双头生理畸形：一例病例报告及文献综述

A Double-Headed Physiologic Monster: A Case Report and Literature Review.

作者信息

Ebuh Valentine, Avila Juan

机构信息

Internal Medicine, Methodist Health System, Dallas, USA.

Internal Medicine, Methodist Dallas Medical Center, Dallas, USA.

出版信息

Cureus. 2023 Aug 30;15(8):e44362. doi: 10.7759/cureus.44362. eCollection 2023 Aug.

DOI:10.7759/cureus.44362
PMID:37654907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10466258/
Abstract

Adrenal incidentaloma (AI) is rare and found in approximately 2-4% of abdominal computed tomography scans. Up to 10% of patients with AI have autonomous secretion of adrenal hormones. If not quickly diagnosed and adequately treated, the outcome may be devastating to the patient. On very rare occasions, a pheochromocytoma may, in addition to the production of catecholamine, produce adrenocorticotropic hormone causing Cushing disease. We present a case of a patient with pheochromocytoma and Cushing syndrome.

摘要

肾上腺偶发瘤（AI）较为罕见，在约2%-4%的腹部计算机断层扫描中被发现。高达10%的肾上腺偶发瘤患者存在肾上腺激素自主分泌。如果不能迅速诊断并得到充分治疗，后果可能对患者极为严重。在极少数情况下，嗜铬细胞瘤除了分泌儿茶酚胺外，还可能分泌促肾上腺皮质激素，导致库欣病。我们报告一例患有嗜铬细胞瘤和库欣综合征的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbcd/10466258/0db1e2d83c92/cureus-0015-00000044362-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbcd/10466258/f3e3f8052707/cureus-0015-00000044362-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbcd/10466258/b5cfbb5a39ba/cureus-0015-00000044362-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbcd/10466258/0db1e2d83c92/cureus-0015-00000044362-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbcd/10466258/f3e3f8052707/cureus-0015-00000044362-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbcd/10466258/b5cfbb5a39ba/cureus-0015-00000044362-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbcd/10466258/0db1e2d83c92/cureus-0015-00000044362-i03.jpg

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A Double-Headed Physiologic Monster: A Case Report and Literature Review.双头生理畸形：一例病例报告及文献综述
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引用本文的文献

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A Secret Revealed: The Coexistence of a Pheochromocytoma and Independent Adrenocorticotropic Hormone-Secreting Cushing Syndrome Within the Same Adrenal Gland.一个秘密被揭开：嗜铬细胞瘤与独立分泌促肾上腺皮质激素的库欣综合征在同一肾上腺内共存。
Cureus. 2025 May 12;17(5):e83943. doi: 10.7759/cureus.83943. eCollection 2025 May.

本文引用的文献

1
Pheochromocytoma and glucoregulation disorders.嗜铬细胞瘤与糖调节紊乱
Ann Afr Med. 2021 Jan-Mar;20(1):42-45. doi: 10.4103/aam.aam_13_20.
2
Will the resection of pheochromocytoma improve preoperative diabetes mellitus?切除嗜铬细胞瘤会改善术前糖尿病吗？
Asian J Surg. 2019 Dec;42(12):990-994. doi: 10.1016/j.asjsur.2019.01.012. Epub 2019 Oct 16.
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Incidental adrenal masses - A primary care approach.偶发肾上腺肿块——初级保健方法
Aust Fam Physician. 2017 Jun;46(6):385-390.
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Resection of Pheochromocytoma Improves Diabetes Mellitus in the Majority of Patients.切除嗜铬细胞瘤可改善大多数患者的糖尿病病情。
Ann Surg Oncol. 2017 May;24(5):1208-1213. doi: 10.1245/s10434-016-5701-6. Epub 2016 Nov 28.
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Diabetes as a marker of pheochromocytoma in hypertensive patients.糖尿病作为高血压患者嗜铬细胞瘤的一个标志物。
J Hypertens. 2003 Sep;21(9):1703-7. doi: 10.1097/00004872-200309000-00020.
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Pheochromocytoma.嗜铬细胞瘤
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Morbidity and mortality in Cushing's disease: an epidemiological approach.库欣病的发病率和死亡率：一种流行病学方法。
Clin Endocrinol (Oxf). 1994 Apr;40(4):479-84. doi: 10.1111/j.1365-2265.1994.tb02486.x.
8
Diabetes mellitus in phaeochromocytoma. Fasting blood glucose levels before and after surgery in 60 patients with phaeochromocytoma.嗜铬细胞瘤中的糖尿病。60例嗜铬细胞瘤患者手术前后的空腹血糖水平。
Acta Endocrinol (Copenh). 1984 Aug;106(4):511-5. doi: 10.1530/acta.0.1060511.