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左氧氟沙星致急性胰腺炎1例罕见病例:病例报告及文献复习

A Rare Case of Levofloxacin-Induced Acute Pancreatitis: Case Report and Literature Review.

作者信息

Omoregie Osahon, Ugwuoke Uyonne T, Agho Osamede, Okonna Uwemedimoh C, Iklaki Winifred U, Okoro Grace C

机构信息

Family and Community Medicine, National Health Service, Glasgow, GBR.

Public Health, East Tennessee State University, Johnson City, USA.

出版信息

Cureus. 2023 Jul 31;15(7):e42743. doi: 10.7759/cureus.42743. eCollection 2023 Jul.

DOI:10.7759/cureus.42743
PMID:37654929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10467605/
Abstract

Diagnosing acute pancreatitis induced by any drug is often overlooked and warrants careful evaluation. Drug-induced acute pancreatitis is relatively rare, and diagnosis of exclusion after ruling out alcohol, gallstones, hypertriglyceridemia, and intervention. Levofloxacin, a class of fluoroquinolones, is generally recommended against various bacterial infections. While levofloxacin is mainly known for its potential side effects, such as photosensitivity and liver toxicity, it can also rarely induce acute pancreatitis. We report a case of acute pancreatitis in a female patient precipitated by levofloxacin. The patient exhibited typical manifestations of acute pancreatitis and had been taking levofloxacin for a urinary tract infection over the past three days. After ruling out other possible causes, her clinical presentation, laboratory results, and imaging findings confirmed levofloxacin-induced acute pancreatitis.

摘要

诊断由任何药物引起的急性胰腺炎常常被忽视,需要仔细评估。药物性急性胰腺炎相对少见,需在排除酒精、胆结石、高甘油三酯血症等因素并排除其他干预因素后进行诊断。左氧氟沙星是一类氟喹诺酮类药物,通常用于治疗各种细菌感染。虽然左氧氟沙星主要以其潜在的副作用如光敏性和肝毒性而闻名,但它也很少能诱发急性胰腺炎。我们报告一例由左氧氟沙星引发的女性急性胰腺炎病例。该患者表现出急性胰腺炎的典型症状,在过去三天因尿路感染一直在服用左氧氟沙星。在排除其他可能原因后,她的临床表现、实验室检查结果和影像学检查结果均证实为左氧氟沙星诱发的急性胰腺炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fde/10467605/e022ad9ceff5/cureus-0015-00000042743-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fde/10467605/9fe7d43f32dc/cureus-0015-00000042743-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fde/10467605/e022ad9ceff5/cureus-0015-00000042743-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fde/10467605/9fe7d43f32dc/cureus-0015-00000042743-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fde/10467605/e022ad9ceff5/cureus-0015-00000042743-i02.jpg

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本文引用的文献

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Levofloxacin-Induced Acute Pancreatitis.左氧氟沙星诱发的急性胰腺炎
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