[接受他莫昔芬治疗的乳腺癌患者血液中类固醇及垂体促激素水平]
[Level of steroid and tropic pituitary hormones in the blood of patients with breast cancer treated with tamoxifen].
作者信息
Kuralasov A K, Togaĭbaeva Z I, Nurmakova S I, Khan O G
出版信息
Vopr Onkol. 1986;32(8):34-8.
PMID:3765507
Abstract
A radioimmunologic assay of steroid and tropic hormones levels in blood serum was carried out in 30 breast cancer patients receiving tamoxifen. Long-term treatment with tamoxifen was followed by a significant decrease in blood-estradiol, progesterone, testosterone and prolactin levels whereas FSH, LH and hydrocortisone concentrations remained virtually unchanged.
摘要
对30名接受他莫昔芬治疗的乳腺癌患者进行了血清中甾体激素和促性腺激素水平的放射免疫分析。长期服用他莫昔芬后，血液中的雌二醇、孕酮、睾酮和催乳素水平显著下降，而促卵泡激素、促黄体生成素和氢化可的松浓度基本保持不变。
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