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[Amplification of myc-specific sequences in human colonic cancer].

作者信息

Serova O M, Shpatar' T V, Fedorov S N, Kniazev P G, Novikov L B

出版信息

Vopr Onkol. 1986;32(8):89-92.

PMID:3765514
Abstract

DNA samples obtained from tumors and adjacent mucosa of the large bowel of a patient with large bowel multiple neoplasia were examined after Southern. The procedure established amplification of v-myc oncogene-related DNA sequences in 1 out of 5 tumors tested. Restriction fragments of amplified myc-specific sequences and matching c-myc and N-myc loci of the human genome differed in size.

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