Neurophysiology Department, Fundación Jiménez Díaz University Hospital, Madrid, Spain.
Internal Medicine Department, La Princesa University Hospital, Madrid, Spain.
Disaster Med Public Health Prep. 2023 Sep 1;17:e475. doi: 10.1017/dmp.2023.152.
To study the respiratory patterns and the hemodynamic variations related to postural changes in inpatients with coronavirus disease (COVID-19).
This report is a prospective study in a cohort of inpatients admitted with COVID-19. We recruited 10 patients admitted to the hospital with moderate or severe COVID-19 who showed improvement in oxygen saturation with prone positioning. We performed cardiorespiratory polygraphy and hemodynamic evaluations by thoracic electrical bioimpedance.
We observed a median minimum oxygen saturation of 85.00% (IQR: 7.00) in the supine position versus 91.00% (IQR: 8.00) ( = 0.173) in the prone position. The airflow restriction in the supine position was 2.70% (IQR: 6.55) versus 1.55% (IQR: 2.80) ( = 0.383) in the prone position. A total of 36.4% of patients were classified as having a normo-hemodynamic state in the supine position, whereas 54.5% were classified in this group in the prone position ( = 0.668). A decrease in vascular resistance was observed in the prone position (18.2% of vasoconstriction) compared to the supine position (36.4% of vasoconstriction) ( = 0.871).
This brief report describes the effects of prone positioning on respiratory and hemodynamic variables in 10 patients with moderate or severe COVID-19.
研究与体位变化相关的冠状病毒病（COVID-19）住院患者的呼吸模式和血液动力学变化。
本报告是一项针对 COVID-19 住院患者的前瞻性研究。我们招募了 10 名因 COVID-19 而住院的患者，这些患者通过俯卧位改善了氧饱和度，表现出改善。我们通过胸部电生物阻抗进行心肺多导睡眠图和血液动力学评估。
我们观察到仰卧位的中位最小氧饱和度为 85.00%（IQR：7.00），而俯卧位为 91.00%（IQR：8.00）（=0.173）。仰卧位的气流受限为 2.70%（IQR：6.55），而俯卧位为 1.55%（IQR：2.80）（=0.383）。36.4%的患者在仰卧位时被归类为血液动力学正常，而 54.5%的患者在俯卧位时被归类为血液动力学正常（=0.668）。与仰卧位相比（血管收缩 36.4%），俯卧位时观察到血管阻力下降（血管收缩 18.2%）（=0.871）。
本简要报告描述了 10 例中重度 COVID-19 患者俯卧位对呼吸和血液动力学变量的影响。
