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高倍显微镜手术中用于高级别胶质瘤安全有效切除的解剖学标志:我的操作方法。

Anatomical landmarks during high-magnification microsurgery for a safe and effective resection of high-grade gliomas: how I do it.

机构信息

Department of Neurosurgery, IRCCS Neuromed, Pozzilli, IS, Italy.

Department of Human Neurosciences, University of Rome "La Sapienza", Rome, Italy.

出版信息

Acta Neurochir (Wien). 2023 Dec;165(12):4235-4240. doi: 10.1007/s00701-023-05723-2. Epub 2023 Sep 1.

DOI:10.1007/s00701-023-05723-2
PMID:37656305
Abstract

BACKGROUND

Gross total resection, when possible, is the first crucial treatment for high-grade gliomas, as it has been demonstrated to be associated with longer survival. Different intraoperative tools, such as neuronavigation, fluorescent agents, and intra-operative ultrasound, have been developed to help neurosurgeons to extend the resection.

METHODS

We describe the high-magnification microsurgery technique used during the first surgical removal for high-grade gliomas. We illustrate the key anatomical "markers" of normal brain parenchyma, which guide the surgery.

CONCLUSION

High-magnification microsurgery is an anatomically based approach that allows the identification of key anatomical "markers" of normal brain parenchyma in order to resect high-grade gliomas safely and effectively.

摘要

背景

最大限度地切除肿瘤,当有可能时,是高级别脑胶质瘤的首要关键治疗方法,因为它已经被证明与更长的生存时间相关。不同的术中工具,如神经导航、荧光剂和术中超声,已经被开发出来,以帮助神经外科医生扩大切除范围。

方法

我们描述了用于高级别脑胶质瘤首次手术切除的高倍显微镜手术技术。我们展示了指导手术的正常脑实质的关键解剖“标志物”。

结论

高倍显微镜手术是一种基于解剖学的方法,它允许识别正常脑实质的关键解剖“标志物”,以便安全有效地切除高级别脑胶质瘤。

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Anatomical landmarks during high-magnification microsurgery for a safe and effective resection of high-grade gliomas: how I do it.高倍显微镜手术中用于高级别胶质瘤安全有效切除的解剖学标志:我的操作方法。
Acta Neurochir (Wien). 2023 Dec;165(12):4235-4240. doi: 10.1007/s00701-023-05723-2. Epub 2023 Sep 1.
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Ultrasound-based real-time neuronavigated fluorescence-guided surgery for high-grade gliomas: technical note and preliminary experience.基于超声的实时神经导航荧光引导手术治疗高级别脑胶质瘤:技术说明和初步经验。
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The Three Pillars of Glioblastoma: A Systematic Review and Novel Analysis of Multi-Omics and Clinical Data.胶质母细胞瘤的三支柱:多组学和临床数据的系统评价及新分析。
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本文引用的文献

1
Continuous subcortical motor evoked potential stimulation using the tip of an ultrasonic aspirator for the resection of motor eloquent lesions.使用超声吸引器尖端进行连续皮质下运动诱发电位刺激以切除运动功能区明确的病变。
J Neurosurg. 2015 Aug;123(2):301-6. doi: 10.3171/2014.11.JNS141555. Epub 2015 May 15.
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The sub-pial resection technique for intrinsic tumor surgery.用于脑实质内肿瘤手术的软脑膜下切除术技术。
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Micro-angiographical studies of the medullary venous system of the cerebral hemisphere.
大脑半球髓质静脉系统的微血管造影研究。
Neuropathology. 1999 Jan;19(1):93-111. doi: 10.1046/j.1440-1789.1999.00215.x.
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Intraoperative localization of subcortical brain lesions.皮质下脑病变的术中定位
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Microvasculature of the human cerebral white matter: arteries of the deep white matter.人类脑白质的微血管系统:深部白质的动脉
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