School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Department of Urology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China.
Medicine (Baltimore). 2023 Sep 1;102(35):e34971. doi: 10.1097/MD.0000000000034971.
Bladder diverticula (BD) can be classified into congenital and acquired forms, with the latter accounting for approximately 90% of all cases, primarily among male patients. Although BD-associated anatomical bladder outlet obstruction (BOO) is uncommon, existing literature suggests that congenital BD are more frequently observed in male children and rarely in female children. While around 70% of acquired BD are linked to BOO secondary to benign prostatic hyperplasia in male patients, clinical reports of female BD are less common. Furthermore, cases of female BD located posterior to the urethra, which lead to voiding difficulties, are exceedingly rare.
Herein, we present a case of laparoscopic treatment in a 53-year-old female patient diagnosed with congenital bladder diverticulum causing progressively worsening dysuria. Voiding cystourethrography revealed a soft cystic protrusion of the posterior urethral wall during voiding, which reinforced the patient's symptoms. Urodynamic examination showed elevated detrusor muscle contraction during voiding, a reduced urinary flow rate, and P/Q values indicative of significant BOO. Considering the patient's clinical condition, we performed laparoscopic bladder diverticulectomy, partial urethral croppingplasty, and cystoplasty.
The laparoscopic bladder diverticulectomy, partial urethral croppingplasty, and cystoplasty procedures were completed thoroughly and with great success. However, complete removal of the diverticular epithelium proved challenging, resulting in an overall operative time of approximately 3 hours and 32 minutes. At the postoperative follow-up, the patient presented with symptoms of a lower urinary tract infection for a week, which were effectively resolved with oral antibiotics. At the 8-month follow-up, the patient reported normal urination and the absence of any discomfort during urination.
Female bladder outlet obstruction resulting from posterior urethral BD can be challenging to visualize during transurethral cystoscopy, especially with limited angulation, and may even be overlooked. Furthermore, conventional transvaginal diverticulectomy is often difficult to perform effectively. Therefore, laparoscopic bladder diverticulectomy, partial urethral croppingplasty, and cystoplasty are considered appropriate treatment options for such cases.
膀胱憩室(BD)可分为先天性和获得性两种形式,后者约占所有病例的 90%,主要发生于男性患者。尽管与 BD 相关的解剖性膀胱出口梗阻(BOO)并不常见,但现有文献表明,先天性 BD 更常见于男童,而在女童中很少见。虽然大约 70%的获得性 BD 与良性前列腺增生导致的 BOO 有关,但女性 BD 的临床报告则较少。此外,位于尿道后方导致排尿困难的女性 BD 病例极为罕见。
在此,我们报告了一例 53 岁女性患者的腹腔镜治疗病例,该患者诊断为先天性膀胱憩室,症状为进行性排尿困难加重。排尿性膀胱尿道造影显示排尿时尿道后壁有一个软性囊性突起,进一步证实了患者的症状。尿动力学检查显示排尿时逼尿肌收缩增高,尿流率降低,P/Q 值提示存在明显的 BOO。鉴于患者的临床情况,我们进行了腹腔镜膀胱憩室切除术、部分尿道裁剪术和膀胱成形术。
腹腔镜膀胱憩室切除术、部分尿道裁剪术和膀胱成形术彻底完成且效果良好。然而,憩室上皮完全切除较为困难,手术总时长约为 3 小时 32 分钟。术后随访时,患者出现下尿路感染症状 1 周,经口服抗生素治疗后有效缓解。8 个月随访时,患者自述排尿正常,排尿时无不适。
女性后尿道 BD 引起的膀胱出口梗阻在经尿道膀胱镜检查时难以观察到,尤其是在角度有限的情况下,甚至可能被忽略。此外,传统的经阴道憩室切除术通常难以有效实施。因此,腹腔镜膀胱憩室切除术、部分尿道裁剪术和膀胱成形术被认为是此类病例的合适治疗选择。