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[白色小鼠面神经肌肉对皮质内微刺激的同侧运动反应]

[Ipsilateral motor responses of the facial muscles to intracortical microstimulation in the white mouse].

作者信息

Lenkov D N, Pronichev I V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1986 Jul-Aug;36(4):744-50.

PMID:3765842
Abstract

Motor responses (MRs) of facial muscles to intracortical microstimulation (ICMS) of lightly anaesthetized outbred white mice were observed visually and recorded by means of photodiodes. ICMS rostral to bregma, within cortical band along sagittal suture (area 6) evoked mostly ipsilateral MRs of vibrissae and upper lip, more often from the left hemisphere. MRs of the lower jaw, tongue and larynx were induced by ICMS in symmetrical zones of both hemispheres. The lowest thresholds of ICMS, 2-20 mcA, were revealed at the depth from 0.8-1.1 mm up to 1.3-1.7 mm, i. e. in layers III and V. Short-latency (from 10 to 25 ms) MRs of the vibrissae, lip and jaw were evoked by high-frequency volleys of 2 to 5 pulses. The participation of some oligosynaptic components in cortico-facial descending projections in the white mouse is supposed.

摘要

在轻度麻醉的远交系白色小鼠中,通过视觉观察并利用光电二极管记录了面部肌肉对皮质内微刺激(ICMS)的运动反应(MRs)。在矢状缝沿线的皮质带(6区)内,前囟前方的ICMS主要诱发同侧触须和上唇的MRs,且更多来自左侧半球。双侧半球对称区域的ICMS可诱发下颌、舌头和喉部的MRs。ICMS的最低阈值为2 - 20毫安,出现在深度为0.8 - 1.1毫米至1.3 - 1.7毫米处,即III层和V层。触须、嘴唇和下颌的短潜伏期(10至25毫秒)MRs由2至5个脉冲的高频脉冲串诱发。推测白色小鼠的皮质 - 面部下行投射中存在一些多突触成分。

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