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[衰老过程中和部分去皮质术后大鼠诱发的皮质-运动反应的变化]

[Changes in evoked cortico-motor responses in the rat during aging and after partial decortication].

作者信息

Ptitsyna I B, Vol'nova A B, Lenkov D N

出版信息

Biull Eksp Biol Med. 1989 Oct;108(10):407-9.

PMID:2597750
Abstract

Some changes of the organization of cortical motor representations, which were revealed by means of the intracortical microstimulation (ICMS) in aged rats after unilateral partial decortication, were true consequences of the decortication, but had no significant relationship to the aging. Distributions of latent periods of contralateral hind-leg EMG-responses to the ICMS had no significant shifts both during aging and after the surgery. Values of short-latency responses of ipsilateral proximal and axial muscles to the ICMS were in late time periods, from 8 to 16 months after surgery, significantly lower than ones of contralateral homonymous muscles. It is supposed, that ipsi- and bilateral short-latency responses to the ICMS in proximal and axial muscles of operated rats during late time periods are relayed through some pathways from the brain stem to the spinal cord.

摘要

通过对单侧部分去皮质老龄大鼠进行皮质内微刺激(ICMS)所揭示的皮质运动代表区组织的一些变化,是去皮质的真实结果,但与衰老并无显著关系。在衰老过程以及手术后,对ICMS的对侧后腿肌电图反应潜伏期的分布均无显著变化。同侧近端和轴向肌肉对ICMS的短潜伏期反应值在手术后8至16个月的后期显著低于对侧同名肌肉。据推测,在后期,手术大鼠近端和轴向肌肉对ICMS的同侧和双侧短潜伏期反应是通过从脑干到脊髓的一些通路中继的。

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