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An autopsy case of dementia and parkinsonism with severe degeneration exclusively in the substantia nigra.

作者信息

Oyanagi K, Nakashima S, Ikuta F, Homma Y

出版信息

Acta Neuropathol. 1986;70(3-4):190-2. doi: 10.1007/BF00686071.

DOI:10.1007/BF00686071
PMID:3766121
Abstract

We have recently encountered a patient with progressive dementia and parkinsonism beginning at the age of 68 years and developing for 2 years. Pathological examination revealed severe degeneration exclusively in the substantia nigra with absence of Lewy bodies and neurofibrillary changes. The features of this case are reported and discussed.

摘要

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Acta Neuropathol. 1986;70(3-4):190-2. doi: 10.1007/BF00686071.
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引用本文的文献

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Juvenile onset Parkinsonism with "pure nigral" degeneration and POLG1 mutation.伴有“单纯黑质”变性和POLG1突变的青少年型帕金森病
Parkinsonism Relat Disord. 2016 Sep;30:83-5. doi: 10.1016/j.parkreldis.2016.06.013. Epub 2016 Jun 21.

本文引用的文献

1
Parkinsonism-dementia complex, an endemic disease on the island of Guam. II. Pathological features.帕金森病痴呆综合征，关岛岛上的一种地方病。II. 病理特征。
Brain. 1961 Dec;84:662-79. doi: 10.1093/brain/84.4.662.
2
Parkinson disease, dementia, and Alzheimer disease: clinicopathological correlations.帕金森病、痴呆与阿尔茨海默病：临床病理相关性
Ann Neurol. 1980 Apr;7(4):329-35. doi: 10.1002/ana.410070408.
3
Basal forebrain neurons in the dementia of Parkinson disease.帕金森病痴呆中的基底前脑神经元。
Ann Neurol. 1983 Mar;13(3):243-8. doi: 10.1002/ana.410130304.
4
New form of familial Parkinson-dementia syndrome: clinical and pathologic findings.家族性帕金森-痴呆综合征的新形式：临床和病理发现
Neurology. 1983 Nov;33(11):1439-43. doi: 10.1212/wnl.33.11.1439.
5
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.帕金森病的灵长类动物模型：N-甲基-4-苯基-1,2,3,6-四氢吡啶对黑质致密部多巴胺能神经元的选择性破坏。
Proc Natl Acad Sci U S A. 1983 Jul;80(14):4546-50. doi: 10.1073/pnas.80.14.4546.
6
Cortical changes in the parkinsonian brain: a contribution to the delineation of "diffuse Lewy body disease".帕金森病大脑的皮质变化：对“弥漫性路易体病”界定的贡献
J Neurol. 1983;229(1):17-32. doi: 10.1007/BF00313493.
7
Dementia in idiopathic Parkinson's disease. A neuropathological study of 32 cases.特发性帕金森病中的痴呆。32例神经病理学研究。
Acta Neuropathol. 1984;64(1):43-52. doi: 10.1007/BF00695605.
8
Parkinson's disease: an environmental cause?帕金森病：由环境因素引起？
Science. 1985 Jul 19;229(4710):257-8. doi: 10.1126/science.3925554.
9
Dementia without Alzheimer pathology.无阿尔茨海默病病理改变的痴呆症
Neurology. 1985 May;35(5):762-5. doi: 10.1212/wnl.35.5.762.
10
Dementia in Parkinson disease: a neuropathologic study.
Neurology. 1979 Sep;29(9 Pt 1):1209-14. doi: 10.1212/wnl.29.9_part_1.1209.