da Silva Márjully Er, de Sena Marina D, Colombo Natália H, Pereira Jesse A, Chrisostomo Daniela A, de Aguiar Sandra Mhcá, Cunha Robson F, Duque Cristiane
Department of Preventive and Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Int J Clin Pediatr Dent. 2023 Aug;16(Suppl 1):S27-S32. doi: 10.5005/jp-journals-10005-2612.
This study evaluated the short-term clinical and microbiological performance of resin-modified glass ionomer cement (RM-GIC) cement containing chlorhexidine (CHX) for atraumatic restorative treatment (ART) in primary teeth.
The clinical trial was conducted in 36 children that received ART in primary molars either with GIC (group I, = 18) or GIC containing 1.25% CHX (group II, = 18). The survival rate of restorations was checked 7 days, 3, and 6 months after their application when saliva and biofilm were collected for microbiological assessment of (MS) counts. Data were analyzed using the Kruskal-Wallis/Mann-Whitney tests for clinical analysis and microbiological evaluations ( < 0.05).
The survival rate of restorations was similar comparing groups I with II. Microbiological analysis showed a significant reduction in MS levels 7 days after the treatment in both saliva and biofilm of children treated with RM-GIC containing CHX (group II); however, MS counts at 3 and 6 months did not differ from the initial counts.
A total of 1.25% CHX improved the microbiological properties of GIC in the short term without impairing the clinical performance of ART restorations.
Glass ionomer cement (GIC) containing CHX could be an alternative in ART procedures with the objective of promoting an additional antimicrobial effect, which is interesting for children with high counts of MS during the initial phase of adaptation to dental treatment.
da Silva ME, de Sena MD, Colombo NH, Short-term Clinical and Microbiological Performance of Resin-modified Glass Ionomer Cement Containing Chlorhexidine for Atraumatic Restorative Treatment. Int J Clin Pediatr Dent 2023;16(S-1):S27-S32.
本研究评估了含氯己定(CHX)的树脂改性玻璃离子水门汀(RM-GIC)用于乳牙非创伤性修复治疗(ART)的短期临床和微生物学性能。
对36名接受乳牙ART治疗的儿童进行临床试验,其中18名儿童使用玻璃离子水门汀(I组),另18名儿童使用含1.25%CHX的玻璃离子水门汀(II组)。在修复体应用后7天、3个月和6个月检查修复体的存留率,同时收集唾液和生物膜进行变形链球菌(MS)计数的微生物学评估。使用Kruskal-Wallis/Mann-Whitney检验对临床分析和微生物学评估数据进行分析(P<0.05)。
I组和II组修复体的存留率相似。微生物学分析显示,在使用含CHX的RM-GIC治疗的儿童(II组)的唾液和生物膜中,治疗7天后MS水平显著降低;然而,3个月和6个月时的MS计数与初始计数无差异。
1.25%的CHX可在短期内改善玻璃离子水门汀的微生物学性能,而不影响ART修复体的临床性能。
含CHX的玻璃离子水门汀可作为ART程序中的一种替代材料,以促进额外的抗菌作用,这对于在适应牙科治疗初始阶段MS计数较高的儿童来说很有意义。
da Silva ME, de Sena MD, Colombo NH, 含氯己定的树脂改性玻璃离子水门汀用于非创伤性修复治疗的短期临床和微生物学性能。《国际临床儿科牙科学杂志》2023;16(S-1):S27-S32。