Torres Adriana da Silva, Martins Olga Beatriz Lopes, Otoni Rejane Pereira, Henrique Soares Kaio, Torres Marcelo Guimarães, Firoozi Parsa, Flecha Olga Dumont
Dentistry Department, Faculty of Biological and Health Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Rua da Glória n° 187, Centro, Diamantina, MG CEP 39100-000, Brazil.
Student Research Committee, School of Dentistry, AJA University of Medical Sciences, Tehran, Iran.
Int J Dent. 2023 Aug 23;2023:1465957. doi: 10.1155/2023/1465957. eCollection 2023.
To compare the effectiveness of cyanoacrylate to other treatments or placebo in the management of dentin hypersensitivity (DH).
The present review was organized based on the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines. The search aimed to answer the following question: is cyanoacrylate effective in the treatment of DH when compared to other treatments or placebo? The following databases were used: PubMed/MEDLINE, Scopus, BVS, Web of Science, Cochrane, Clinicaltrials.gov, Portal Periódicos Capes, Google Scholar, and manual search. The evaluation process started with the information collected from the selected articles according to the Consolidated Standards of Reporting Trials (CONSORT).
Two randomized and five nonrandomized clinical trials were analyzed in the qualitative synthesis. The studies presented different cyanoacrylate formulations, different scales for evaluating pain, and different methods for provoking a painful stimulus. Cyanoacrylate-based products reduce DH in shorter follow-up periods and this reduction persisted throughout the study. The results varied according to the methods used to stimulate the pain. Only two articles showed a low risk of bias and a high level of scientific evidence.
Although there is a limited number of studies in the scientific literature with appropriate methodological quality, the available evidence proves the effectiveness of cyanoacrylate in the treatment of DH. . Cyanoacrylate is easy to access, effective, easily applicable, and a low-cost product with satisfactory results.
比较氰基丙烯酸酯与其他治疗方法或安慰剂在治疗牙本质过敏症(DH)方面的有效性。
本综述是根据系统评价和Meta分析的首选报告项目(PRISMA)指南进行组织的。该检索旨在回答以下问题:与其他治疗方法或安慰剂相比,氰基丙烯酸酯在治疗DH方面是否有效?使用了以下数据库:PubMed/MEDLINE、Scopus、BVS、科学网、Cochrane、Clinicaltrials.gov、Capes期刊门户、谷歌学术搜索以及手动检索。评估过程从根据试验报告的统一标准(CONSORT)从所选文章中收集的信息开始。
在定性综合分析中分析了两项随机临床试验和五项非随机临床试验。这些研究呈现了不同的氰基丙烯酸酯配方、不同的疼痛评估量表以及不同的引发疼痛刺激的方法。基于氰基丙烯酸酯的产品在较短的随访期内可减轻DH,且这种减轻在整个研究过程中持续存在。结果因用于刺激疼痛的方法而异。只有两篇文章显示出低偏倚风险和高水平的科学证据。
尽管科学文献中方法学质量合适的研究数量有限,但现有证据证明氰基丙烯酸酯在治疗DH方面是有效的。氰基丙烯酸酯易于获取、有效、易于应用,是一种低成本产品,效果令人满意。