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癌症患者中抑郁症和焦虑症的患病率:来自单一机构的见解

Prevalence of Depression and Anxiety Disorders Among Cancer Patients: An Insight From a Single Institute.

作者信息

Radhakrishnan Remya, Selvaraj Hemalatha, Chidambaram Kumarappan, Kv Arshav, James Adona, Thangavel Sivakumar

机构信息

Pharmacy Practice, Nandha College of Pharmacy, Erode, IND.

Pharmacology & Toxicology, King Khalid University, Abha, SAU.

出版信息

Cureus. 2023 Aug 1;15(8):e42831. doi: 10.7759/cureus.42831. eCollection 2023 Aug.

Abstract

Objective This cross-sectional, observational study aimed at finding the prevalence of anxiety and depression in cancer patients and the correlation of anxiety and depression with various factors, such as age, sex, marital status, educational status, occupation, financial support, duration, type of care, sort of carcinoma, and stages of malignancy, among cancer patients attending the G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, Tamil Nadu, India from July 2022 to December 2022, using the Hospital Anxiety and Depression Scale (HADS). Methods A total of 162 cancer patients referred for various cancer therapies (chemo/surgery/combination therapies) were included. All patients were administered the HADS. The association between anxiety scores and various factors such as age, site, and sex was found using the chi-square test. Results Thirty-nine (24.1%) patients had severe anxiety, 60 (37%) patients had borderline anxiety, and 63 (38.9%) patients were found to be normal. Fifty-three (32.7%) patients had severe depression, 47 (29%) patients had borderline depression, and 62 (38.3%) patients were found to be normal. The findings of this study indicate that educational status and occupational status are the significant factors (p < 0.05) responsible for increasing the risk of prevalence of anxiety and depression in cancer patients. Another interesting observation in this study was that patients with breast and gastrointestinal cancer had the highest prevalence of depression among other cancer types. Conclusions The present study contributed to the prevalence of anxiety and depression in cancer patients in Tamil Nadu, India. While the study population is small, which is a limitation of the present study, it has provided an overview that educational status and occupation contribute significantly to anxiety and depression, which has not been explored much in the past. To efficiently manage this, patients should be made aware of the financial support available from various philanthropic groups, government policies, and insurance so that they can improve their quality of life and manage their clinical condition in a more confident manner. These findings call for the need for early psychiatric interventions in cancer care to improve the quality of life of patients by focusing on improving patients' mental stability and adherence to the medications for providing positive outcomes from the cancer treatments.

摘要

目的 这项横断面观察性研究旨在通过医院焦虑抑郁量表(HADS),找出印度泰米尔纳德邦哥印拜陀市G. 库普斯瓦米·奈杜纪念医院2022年7月至2022年12月期间癌症患者中焦虑和抑郁的患病率,以及焦虑和抑郁与年龄、性别、婚姻状况、教育程度、职业、经济支持、病程、护理类型、癌症类型和恶性肿瘤分期等各种因素之间的相关性。方法 共纳入162名因各种癌症治疗(化疗/手术/联合治疗)前来就诊的癌症患者。所有患者均接受HADS评估。采用卡方检验分析焦虑评分与年龄、部位、性别等各种因素之间的关联。结果 39名(24.1%)患者存在严重焦虑,60名(37%)患者存在临界焦虑,63名(38.9%)患者正常。53名(32.7%)患者存在严重抑郁,47名(29%)患者存在临界抑郁,62名(38.3%)患者正常。本研究结果表明,教育程度和职业状况是导致癌症患者焦虑和抑郁患病率增加的重要因素(p<0.05)。本研究的另一个有趣发现是,乳腺癌和胃肠道癌患者的抑郁患病率在其他癌症类型中最高。结论 本研究有助于了解印度泰米尔纳德邦癌症患者焦虑和抑郁的患病率。虽然本研究的样本量较小,这是本研究的一个局限性,但它提供了一个概述,即教育程度和职业对焦虑和抑郁有显著影响,而这在过去并未得到充分探讨。为了有效管理这一情况,应让患者了解各种慈善团体、政府政策和保险提供的经济支持,以便他们能够提高生活质量并更自信地管理自己的临床状况。这些发现呼吁在癌症护理中需要早期精神科干预,通过关注改善患者的心理稳定性和坚持用药,以从癌症治疗中获得积极结果,从而提高患者的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8913/10472014/cf60e75191a9/cureus-0015-00000042831-i01.jpg

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