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一种神秘的复发性荨麻疹皮疹与一种改变人生的金属

A Mysterious Recurrent Urticarial Rash and a Life-Altering Metal.

作者信息

Friedman Adam, Schweiker-Kahn Olga, Roy Satyajeet

机构信息

Medicine, Cooper Medical School of Rowan University, Camden, USA.

Internal Medicine, Cooper University Hospital, Camden, USA.

出版信息

Cureus. 2023 Aug 31;15(8):e44469. doi: 10.7759/cureus.44469. eCollection 2023 Aug.

DOI:10.7759/cureus.44469
PMID:37664360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10473443/
Abstract

Allergic contact dermatitis is a common manifestation in individuals who have a contact hypersensitivity to nickel. Direct exposure to nickel triggers an adaptive immune response that mediates a localized inflammatory reaction of the skin, typically resulting in an erythematous and pruritic rash at the site of contact. We present a distinct case in which nickel was systemically introduced via a carotid stent into an individual with an unidentified allergy to nickel. This case emphasizes the potentially life-threatening risks associated with implantable hardware containing metals, such as nickel. Moreover, this case highlights the potential benefit that screening for metal allergies may have before surgically implanting permanent metal-based devices.

摘要

过敏性接触性皮炎是对镍有接触性超敏反应的个体的常见表现。直接接触镍会引发适应性免疫反应,介导皮肤的局部炎症反应,通常在接触部位导致红斑和瘙痒性皮疹。我们报告了一例独特的病例,其中镍通过颈动脉支架被全身引入一名对镍过敏但未确诊的个体。该病例强调了与含镍等金属的植入性硬件相关的潜在危及生命的风险。此外,该病例突出了在手术植入永久性金属基设备之前筛查金属过敏可能具有的潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6bb/10473443/eaa648f1c6cf/cureus-0015-00000044469-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6bb/10473443/eaa648f1c6cf/cureus-0015-00000044469-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6bb/10473443/eaa648f1c6cf/cureus-0015-00000044469-i01.jpg

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A comprehensive summary of disease variants implicated in metal allergy.金属过敏相关疾病变异体的综合总结。
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